HSPA4 and ST13

Number of citations of the paper that reports this interaction (PubMedID 27708256)
25

Data Source:
BioGRID (pull down, affinity chromatography technology, pull down)

		HSPA4	ST13
Description		heat shock protein family A (Hsp70) member 4	ST13 Hsp70 interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Extracellular Exosome	Cytoplasm Cytosol Protein-containing Complex Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding	Protein Binding Protein Domain Specific Binding Hsp70 Protein Binding Protein Binding, Bridging Heat Shock Protein Binding DATP Binding Identical Protein Binding Protein-containing Complex Binding Protein Dimerization Activity Unfolded Protein Binding Chaperone Binding
	Biological Process	Response To Unfolded Protein Protein Import Into Mitochondrial Outer Membrane Chaperone-mediated Protein Complex Assembly	Protein Folding Response To Bacterium Chaperone Cofactor-dependent Protein Refolding Chaperone-mediated Protein Folding Negative Regulation Of Protein Refolding Protein-containing Complex Assembly
Pathways		Regulation of HSF1-mediated heat shock response	Regulation of HSF1-mediated heat shock response
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Breast cancer ( 29059683) Chronic obstructive pulmonary disease ( 30804561) Diastolic blood pressure ( 30224653) Eyebrow thickness ( 26926045) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Reticulocyte fraction of red cells ( 27863252) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Feeling nervous ( 29500382)
Interacting Genes		65 interacting genes: ABCC2 AGTRAP APPBP2 BAG1 BAG2 BAG5 BRMS1 CALM1 CD40 CDC73 CDKN2A CSNK1A1 CSNK2A1 DDIT4 DNAJB1 DNAJB2 DUSP1 EGFR ESR1 FANCC FES FKBP4 GATA1 GRPEL2 GSK3B GZMA HAP1 HDAC3 HNRNPD HSPB1 HSPBP1 IKBKG KPNA2 KRT18 MUC1 NAA10 NFKB1 NR3C2 OLR1 PA2G4 PHLDA1 PPP1CA PRKACA PRKCB PRKCD PRKCG PRSS23 PSMD10 RAF1 RAP1A REL RELA SGTA SIRPA SMAD3 ST13 STUB1 SUGT1 TERT TOMM40 TRAF6 TRIM32 TTC1 UBE2L3 UBE3A	18 interacting genes: ALB APOE ASF1A CD101 CDC42 CTRC CXCR2 F2 HSP90AA1 HSPA1A HSPA4 HSPA8 NOS3 OLFM2 PSEN1 SMAD2 TTR VAV2
Entrez ID		3308	6767
HPRD ID		09025	08426
Ensembl ID		ENSG00000170606	ENSG00000100380
Uniprot IDs		P34932	A0A140VKA6 B4E0U6 P50502 Q0IJ56
PDB IDs			1UZS
Enriched GO Terms of Interacting Partners?
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