GPRASP2 and CBX8

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GPRASP2	CBX8
Description		G protein-coupled receptor associated sorting protein 2	chromobox 8
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nuclear Chromatin Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding	Single-stranded RNA Binding Protein Binding Methylated Histone Binding Ubiquitin-protein Transferase Activator Activity
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Proliferation Histone Ubiquitination Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of DNA Repair Regulation Of Catalytic Activity Cellular Response To Hydrogen Peroxide
Pathways			Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS			General risk tolerance (MTAG) ( 30643258) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		29 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CBX8 CEP126 CFAP206 CHRM1 CHRM2 DISC1 FRAT1 HAP1 HRH2 HTR7 HTT LRIF1 MICU2 MYOT NOL4L-DT PRPF3 PTN RPS6KA5 RTL10 STMN2 TCF25 TSPOAP1 TXN TXN2 ZNF688	36 interacting genes: BMI1 CALCOCO2 CCDC136 CCDC57 EEF1G FSD2 GOLGA2 GPRASP2 H3-4 HAP1 HMBOX1 IKZF1 KAT5 KAT7 KCTD9 KIFC3 KRT40 LZTS2 MID2 MLLT1 MLLT3 MTUS2 PAXIP1 PCGF5 PNMA2 RING1 RPGRIP1 SETDB1 SOX5 TFCP2 TRAF2 TSGA10 UNC119 USP11 USP7 ZBTB14
Entrez ID		114928	57332
HPRD ID		06612	13006
Ensembl ID		ENSG00000158301	ENSG00000141570
Uniprot IDs		B3KW05 Q96D09	Q9HC52
PDB IDs			2N4Q 3I91 5EQ0
Enriched GO Terms of Interacting Partners?
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