GPRASP2 and MYOT

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GPRASP2	MYOT
Description		G protein-coupled receptor associated sorting protein 2	myotilin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Plasma Membrane Actin Cytoskeleton Z Disc Axon Sarcolemma Neuronal Cell Body
	Molecular Function	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding	Actin Binding Protein Binding Axon Guidance Receptor Activity Structural Constituent Of Muscle Alpha-actinin Binding
	Biological Process		Muscle Contraction Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Synapse Organization
Pathways
Drugs
Diseases			Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy Limb-girdle muscular dystrophy (LGMD)
GWAS			Atrial fibrillation ( 30061737) Heart rate ( 23583979) Severe malaria ( 29381699) Severe malaria (adjusted for sickle cell variant rs334) ( 29381699)
Interacting Genes		29 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CBX8 CEP126 CFAP206 CHRM1 CHRM2 DISC1 FRAT1 HAP1 HRH2 HTR7 HTT LRIF1 MICU2 MYOT NOL4L-DT PRPF3 PTN RPS6KA5 RTL10 STMN2 TCF25 TSPOAP1 TXN TXN2 ZNF688	13 interacting genes: ACTN1 ACTN2 APP AXIN1 FLNA FLNC GPRASP2 LRP12 NME7 ST7 TFG TRIM55 TRIM63
Entrez ID		114928	9499
HPRD ID		06612	04981
Ensembl ID		ENSG00000158301	ENSG00000120729
Uniprot IDs		B3KW05 Q96D09	A0A0C4DFM5 B4DT68 Q9UBF9
PDB IDs			2KDG 2KKQ
Enriched GO Terms of Interacting Partners?
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