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CCNA1 |
cyclin A1 |
- G0 and Early G1
- Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
- Telomere Extension By Telomerase
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Regulation of APC/C activators between G1/S and early anaphase
- SCF(Skp2)-mediated degradation of p27/p21
- Senescence-Associated Secretory Phenotype (SASP)
- DNA Damage/Telomere Stress Induced Senescence
- Ub-specific processing proteases
- Processing of DNA double-strand break ends
- TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
- Regulation of TP53 Activity through Phosphorylation
- Regulation of TP53 Degradation
- G2 Phase
- Orc1 removal from chromatin
- CDK-mediated phosphorylation and removal of Cdc6
- G1/S-Specific Transcription
- Cyclin A/B1/B2 associated events during G2/M transition
- Cyclin A/B1/B2 associated events during G2/M transition
- p53-Dependent G1 DNA Damage Response
- Cyclin A:Cdk2-associated events at S phase entry
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CD2AP |
CD2 associated protein |
- Nephrin family interactions
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- Nephrotic syndrome and focal segmental glomerulosclerosis
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CD36 |
CD36 molecule |
- Platelet degranulation
- Cross-presentation of particulate exogenous antigens (phagosomes)
- ER-Phagosome pathway
- MyD88:MAL(TIRAP) cascade initiated on plasma membrane
- Toll Like Receptor TLR6:TLR2 Cascade
- PPARA activates gene expression
- Scavenging by Class B Receptors
- Scavenging by Class B Receptors
- Transcriptional regulation of white adipocyte differentiation
- Intracellular metabolism of fatty acids regulates insulin secretion
- MyD88 deficiency (TLR2/4)
- IRAK4 deficiency (TLR2/4)
- Regulation of TLR by endogenous ligand
- Interleukin-4 and Interleukin-13 signaling
- Neutrophil degranulation
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CD46 |
CD46 molecule |
- Regulation of Complement cascade
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CD59 |
CD59 molecule (CD59 blood group) |
- COPII-mediated vesicle transport
- Cargo concentration in the ER
- Neutrophil degranulation
- COPI-mediated anterograde transport
- Regulation of Complement cascade
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- Complement regulatory protein defects, including the following six diseases: C1 inhibitor deficiency (hereditary angioedema); C4 binding protein alpha deficiency; C4 binding protein beta deficiency; Factor I deficiency; Decay-accelerating factor (CD55) deficiency; CD59 deficiency
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CDC25A |
cell division cycle 25A |
- Transcription of E2F targets under negative control by DREAM complex
- Polo-like kinase mediated events
- Activation of ATR in response to replication stress
- Ub-specific processing proteases
- Cyclin E associated events during G1/S transition
- Cyclin A/B1/B2 associated events during G2/M transition
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
- Cyclin A:Cdk2-associated events at S phase entry
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
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CDC37 |
cell division cycle 37, HSP90 cochaperone |
- Signaling by ERBB2
- Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
- Constitutive Signaling by EGFRvIII
- Regulation of necroptotic cell death
- Downregulation of ERBB2 signaling
- RHOBTB2 GTPase cycle
- Constitutive Signaling by Overexpressed ERBB2
- Drug-mediated inhibition of ERBB2 signaling
- Signaling by ERBB2 KD Mutants
- Resistance of ERBB2 KD mutants to trastuzumab
- Resistance of ERBB2 KD mutants to sapitinib
- Resistance of ERBB2 KD mutants to tesevatinib
- Resistance of ERBB2 KD mutants to neratinib
- Resistance of ERBB2 KD mutants to osimertinib
- Resistance of ERBB2 KD mutants to afatinib
- Resistance of ERBB2 KD mutants to AEE788
- Resistance of ERBB2 KD mutants to lapatinib
- Signaling by ERBB2 ECD mutants
- Signaling by ERBB2 TMD/JMD mutants
- Drug resistance in ERBB2 TMD/JMD mutants
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CDCP1 |
CUB domain containing protein 1 |
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CDKN1B |
cyclin dependent kinase inhibitor 1B |
- SCF(Skp2)-mediated degradation of p27/p21
- AKT phosphorylates targets in the cytosol
- Senescence-Associated Secretory Phenotype (SASP)
- DNA Damage/Telomere Stress Induced Senescence
- RHO GTPases activate CIT
- Constitutive Signaling by AKT1 E17K in Cancer
- TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
- Cyclin E associated events during G1/S transition
- Cyclin D associated events in G1
- p53-Dependent G1 DNA Damage Response
- Cyclin A:Cdk2-associated events at S phase entry
- PTK6 Regulates Cell Cycle
- FLT3 Signaling
- FOXO-mediated transcription of cell cycle genes
- Estrogen-dependent nuclear events downstream of ESR-membrane signaling
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
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CEACAM3 |
CEA cell adhesion molecule 3 |
- Cell surface interactions at the vascular wall
- Neutrophil degranulation
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CLTC |
clathrin heavy chain |
- Entry of Influenza Virion into Host Cell via Endocytosis
- Retrograde neurotrophin signalling
- Retrograde neurotrophin signalling
- Gap junction degradation
- Formation of annular gap junctions
- MHC class II antigen presentation
- EPH-ephrin mediated repulsion of cells
- Lysosome Vesicle Biogenesis
- Recycling pathway of L1
- Recycling pathway of L1
- WNT5A-dependent internalization of FZD4
- WNT5A-dependent internalization of FZD2, FZD5 and ROR2
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- VLDLR internalisation and degradation
- LDL clearance
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CNTNAP1 |
contactin associated protein 1 |
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COASY |
Coenzyme A synthase |
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CORO7 |
coronin 7 |
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CRMP1 |
collapsin response mediator protein 1 |
- CRMPs in Sema3A signaling
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CTNND1 |
catenin delta 1 |
- Adherens junctions interactions
- VEGFR2 mediated vascular permeability
- InlA-mediated entry of Listeria monocytogenes into host cells
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CTTN |
cortactin |
- RHO GTPases activate PAKs
- Clathrin-mediated endocytosis
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DAB1 |
DAB adaptor protein 1 |
- Reelin signalling pathway
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DAB2 |
DAB adaptor protein 2 |
- Gap junction degradation
- Formation of annular gap junctions
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
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DAG1 |
dystroglycan 1 |
- Non-integrin membrane-ECM interactions
- ECM proteoglycans
- ECM proteoglycans
- Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3
- Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2
- Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1
- O-linked glycosylation
- Regulation of expression of SLITs and ROBOs
- EGR2 and SOX10-mediated initiation of Schwann cell myelination
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- Limb-girdle muscular dystrophy (LGMD)
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