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FBXW11 |
F-box and WD repeat domain containing 11 |
- Activation of NF-kappaB in B cells
- Downstream TCR signaling
- Regulation of PLK1 Activity at G2/M Transition
- FCERI mediated NF-kB activation
- Dectin-1 mediated noncanonical NF-kB signaling
- CLEC7A (Dectin-1) signaling
- NIK-->noncanonical NF-kB signaling
- MAP3K8 (TPL2)-dependent MAPK1/3 activation
- Neddylation
- Antigen processing: Ubiquitination & Proteasome degradation
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FOXK1 |
forkhead box K1 |
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FUBP3 |
far upstream element binding protein 3 |
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GEMIN4 |
gem nuclear organelle associated protein 4 |
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GNAI1 |
G protein subunit alpha i1 |
- PLC beta mediated events
- PLC beta mediated events
- Adenylate cyclase inhibitory pathway
- Adenylate cyclase inhibitory pathway
- G-protein activation
- ADP signalling through P2Y purinoceptor 12
- Adrenaline,noradrenaline inhibits insulin secretion
- Adrenaline,noradrenaline inhibits insulin secretion
- G alpha (s) signalling events
- G alpha (i) signalling events
- G alpha (i) signalling events
- G alpha (z) signalling events
- Regulation of insulin secretion
- Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
- Extra-nuclear estrogen signaling
- ADORA2B mediated anti-inflammatory cytokines production
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- Guanosine-5'-Diphosphate
- Tetrafluoroaluminate Ion
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GNAI2 |
G protein subunit alpha i2 |
- PLC beta mediated events
- PLC beta mediated events
- Adenylate cyclase inhibitory pathway
- Adenylate cyclase inhibitory pathway
- G-protein activation
- ADP signalling through P2Y purinoceptor 12
- Adrenaline,noradrenaline inhibits insulin secretion
- Adrenaline,noradrenaline inhibits insulin secretion
- G alpha (s) signalling events
- G alpha (i) signalling events
- G alpha (i) signalling events
- G alpha (z) signalling events
- Regulation of insulin secretion
- Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
- Extra-nuclear estrogen signaling
- ADORA2B mediated anti-inflammatory cytokines production
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GNB4 |
G protein subunit beta 4 |
- Activation of G protein gated Potassium channels
- Glucagon signaling in metabolic regulation
- G-protein activation
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
- ADP signalling through P2Y purinoceptor 12
- G beta:gamma signalling through PI3Kgamma
- Prostacyclin signalling through prostacyclin receptor
- Prostacyclin signalling through prostacyclin receptor
- Adrenaline,noradrenaline inhibits insulin secretion
- Adrenaline,noradrenaline inhibits insulin secretion
- Ca2+ pathway
- Ca2+ pathway
- G alpha (q) signalling events
- G alpha (12/13) signalling events
- G beta:gamma signalling through PLC beta
- G alpha (s) signalling events
- ADP signalling through P2Y purinoceptor 1
- ADP signalling through P2Y purinoceptor 1
- G alpha (i) signalling events
- G alpha (z) signalling events
- Glucagon-type ligand receptors
- Thromboxane signalling through TP receptor
- Vasopressin regulates renal water homeostasis via Aquaporins
- Thrombin signalling through proteinase activated receptors (PARs)
- Thrombin signalling through proteinase activated receptors (PARs)
- Presynaptic function of Kainate receptors
- Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
- G beta:gamma signalling through BTK
- G beta:gamma signalling through CDC42
- Extra-nuclear estrogen signaling
- ADORA2B mediated anti-inflammatory cytokines production
- Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
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GNL3 |
G protein nucleolar 3 |
- Major pathway of rRNA processing in the nucleolus and cytosol
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GPC4 |
glypican 4 |
- A tetrasaccharide linker sequence is required for GAG synthesis
- HS-GAG biosynthesis
- HS-GAG biosynthesis
- HS-GAG degradation
- Defective B4GALT7 causes EDS, progeroid type
- Defective B3GAT3 causes JDSSDHD
- Defective EXT2 causes exostoses 2
- Defective EXT1 causes exostoses 1, TRPS2 and CHDS
- Defective B3GALT6 causes EDSP2 and SEMDJL1
- Retinoid metabolism and transport
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GSTM2 |
glutathione S-transferase mu 2 |
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- Glutathione
- S-(2,4-dinitrophenyl)glutathione
- Glutathione disulfide
- Glutathione disulfide
- S-Methyl glutathione
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GTF3C2 |
general transcription factor IIIC subunit 2 |
- RNA Polymerase III Abortive And Retractive Initiation
- RNA Polymerase III Transcription Initiation From Type 1 Promoter
- RNA Polymerase III Transcription Initiation From Type 1 Promoter
- RNA Polymerase III Transcription Initiation From Type 2 Promoter
- RNA Polymerase III Transcription Initiation From Type 2 Promoter
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GTF3C3 |
general transcription factor IIIC subunit 3 |
- RNA Polymerase III Abortive And Retractive Initiation
- RNA Polymerase III Transcription Initiation From Type 1 Promoter
- RNA Polymerase III Transcription Initiation From Type 1 Promoter
- RNA Polymerase III Transcription Initiation From Type 2 Promoter
- RNA Polymerase III Transcription Initiation From Type 2 Promoter
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GTF3C5 |
general transcription factor IIIC subunit 5 |
- RNA Polymerase III Abortive And Retractive Initiation
- RNA Polymerase III Transcription Initiation From Type 1 Promoter
- RNA Polymerase III Transcription Initiation From Type 1 Promoter
- RNA Polymerase III Transcription Initiation From Type 2 Promoter
- RNA Polymerase III Transcription Initiation From Type 2 Promoter
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H2AC4 |
H2A clustered histone 4 |
- Recognition and association of DNA glycosylase with site containing an affected pyrimidine
- Cleavage of the damaged pyrimidine
- Recognition and association of DNA glycosylase with site containing an affected purine
- Recognition and association of DNA glycosylase with site containing an affected purine
- Cleavage of the damaged purine
- Cleavage of the damaged purine
- Meiotic synapsis
- Packaging Of Telomere Ends
- Pre-NOTCH Transcription and Translation
- Formation of the beta-catenin:TCF transactivating complex
- Formation of the beta-catenin:TCF transactivating complex
- PRC2 methylates histones and DNA
- Condensation of Prophase Chromosomes
- Oxidative Stress Induced Senescence
- Senescence-Associated Secretory Phenotype (SASP)
- DNA Damage/Telomere Stress Induced Senescence
- HDACs deacetylate histones
- HATs acetylate histones
- HATs acetylate histones
- RMTs methylate histone arginines
- SIRT1 negatively regulates rRNA expression
- ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
- NoRC negatively regulates rRNA expression
- NoRC negatively regulates rRNA expression
- B-WICH complex positively regulates rRNA expression
- DNA methylation
- Transcriptional regulation by small RNAs
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- UCH proteinases
- Ub-specific processing proteases
- Metalloprotease DUBs
- Deposition of new CENPA-containing nucleosomes at the centromere
- RNA Polymerase I Promoter Opening
- RNA Polymerase I Promoter Escape
- RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Estrogen-dependent gene expression
- Meiotic recombination
- HCMV Early Events
- HCMV Late Events
- Transcriptional regulation of granulopoiesis
- Inhibition of DNA recombination at telomere
- Amyloid fiber formation
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HADHA |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
- Acyl chain remodeling of CL
- Beta oxidation of myristoyl-CoA to lauroyl-CoA
- mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
- Beta oxidation of palmitoyl-CoA to myristoyl-CoA
- Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
- Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
- Beta oxidation of octanoyl-CoA to hexanoyl-CoA
- Beta oxidation of hexanoyl-CoA to butanoyl-CoA
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- Disorders of fatty-acid oxidation, including: Medium-chain (MC) acyl-CoA dehydrogenase (AD) deficiency (MCADD); Short-chain AD deficiency (SCADD) ; Short-branched-chain AD deficiency (SBCADD) ; Very long-chain AD deficiency (VLCADD) ; Long-chain 3-hydroxyacyl CoA dehydrogenase deficiency (LCHADD) ; Trifunctional protein deficiency (TFP); Carnitine palmitoyltransferase deficiency (CPT); Carnitine-acylcarnitine translocase deficiency (CACT); Systemic primary carnitine deficiency (CDSP)
- Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
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HBA1 |
hemoglobin subunit alpha 1 |
- Erythrocytes take up carbon dioxide and release oxygen
- Erythrocytes take up oxygen and release carbon dioxide
- Scavenging of heme from plasma
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- Iron Dextran
- Iron
- Zinc
- 4-Carboxycinnamic Acid
- Pentaerythritol tetranitrate
- 2-[(2-methoxy-5-methylphenoxy)methyl]pyridine
- 4-[(5-methoxy-2-methylphenoxy)methyl]pyridine
- Sebacic acid
- 2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID
- 2,6-dicarboxynaphthalene
- Efaproxiral
- Trimesic acid
- Nitrous acid
- Copper
- Ferric pyrophosphate
- Sodium ferric gluconate complex
- Ferrous sulfate anhydrous
- Ferric pyrophosphate citrate
- Zinc acetate
- Ferrous gluconate
- Ferrous succinate
- Ferrous ascorbate
- Ferrous fumarate
- Ferrous glycine sulfate
- Zinc chloride
- Zinc sulfate, unspecified form
- Voxelotor
- Ferric derisomaltose
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- Thalassemia; Alpha thalassemia; Beta thalassemia; Alpha thalassemia, X-linked (ATRX)
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HNRNPA1 |
heterogeneous nuclear ribonucleoprotein A1 |
- FGFR2 alternative splicing
- mRNA Splicing - Major Pathway
- Processing of Capped Intron-Containing Pre-mRNA
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HNRNPA3 |
heterogeneous nuclear ribonucleoprotein A3 |
- mRNA Splicing - Major Pathway
- Processing of Capped Intron-Containing Pre-mRNA
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HNRNPAB |
heterogeneous nuclear ribonucleoprotein A/B |
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HNRNPUL1 |
heterogeneous nuclear ribonucleoprotein U like 1 |
- mRNA Splicing - Major Pathway
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