Search Results for: ESR1

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
RAC3 Rac family small GTPase 3
  • Rho GTPase cycle
  • PCP/CE pathway
RGS3 regulator of G protein signaling 3
  • G alpha (q) signalling events
  • G alpha (i) signalling events
RNF4 ring finger protein 4
  • Processing of DNA double-strand break ends
  • Antigen processing: Ubiquitination & Proteasome degradation
SET SET nuclear proto-oncogene
  • Condensation of Prophase Chromosomes
  • HuR (ELAVL1) binds and stabilizes mRNA
SFPQ splicing factor proline and glutamine rich
  • PTK6 Regulates Proteins Involved in RNA Processing
  • Suppression of apoptosis
  • Copper
  • Artenimol
SKIL SKI like proto-oncogene
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  • RMTs methylate histone arginines
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
  • RMTs methylate histone arginines
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • RMTs methylate histone arginines
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • Phenethyl Isothiocyanate
SMYD2 SET and MYND domain containing 2
  • PKMTs methylate histone lysines
  • Regulation of TP53 Activity through Methylation
SREBF1 sterol regulatory element binding transcription factor 1
  • RORA activates gene expression
  • FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
  • Doconexent
  • Omega-3-acid ethyl esters
  • Omega-3 fatty acids
  • Fish oil
SUV39H1 suppressor of variegation 3-9 homolog 1
  • PKMTs methylate histone lysines
  • SIRT1 negatively regulates rRNA expression
TADA3 transcriptional adaptor 3
  • HATs acetylate histones
  • Ub-specific processing proteases
THRB thyroid hormone receptor beta
  • Nuclear Receptor transcription pathway
  • SUMOylation of intracellular receptors
  • Liothyronine
  • Levothyroxine
  • Dextrothyroxine
  • Amiodarone
  • Liotrix
  • [3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid
  • KB-141
  • 2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione
  • Tiratricol
  • GC-24
  • Eprotirome
  • MB07811
  • Sobetirome
  • 1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE
  • Thyroid, porcine
WIPI1 WD repeat domain, phosphoinositide interacting 1
  • Macroautophagy
  • XBP1(S) activates chaperone genes
ZBTB16 zinc finger and BTB domain containing 16
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
  • Skeletal defects, genital hypoplasia, and mental retardation
  • Acute myeloid leukemia (AML)
ATAD2 ATPase family AAA domain containing 2
  • TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
BAG1 BAG cochaperone 1
  • Regulation of HSF1-mediated heat shock response
  • (2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
BCAS2 BCAS2 pre-mRNA processing factor
  • mRNA Splicing - Major Pathway
CBLL1 Cbl proto-oncogene like 1
  • InlA-mediated entry of Listeria monocytogenes into host cells

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