Search Results for: ESR1

371 interactions involving ESR1 - estrogen receptor 1 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
JUNB JunB proto-oncogene, AP-1 transcription factor subunit
  • SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
  • Interleukin-4 and Interleukin-13 signaling
  • NGF-stimulated transcription
  • NGF-stimulated transcription
MED10 mediator complex subunit 10
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
MED12 mediator complex subunit 12
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • FG syndrome (FGS); Opitz-Kaveggia syndrome
  • MED12-related disorders, including: Lujan-Fryns syndrome (LFS); Lujan syndrome; X-linked mental retardation with Marfanoid habitus; FG syndrome type 1 (FGS1); Opitz-Kaveggia syndrome
MED13 mediator complex subunit 13
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
MED14 mediator complex subunit 14
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
MED16 mediator complex subunit 16
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
MED17 mediator complex subunit 17
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
MED20 mediator complex subunit 20
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
MED23 mediator complex subunit 23
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
MED24 mediator complex subunit 24
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
MED27 mediator complex subunit 27
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
MED6 mediator complex subunit 6
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
MED7 mediator complex subunit 7
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
NUDT21 nudix hydrolase 21
  • mRNA Splicing - Major Pathway
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
  • Processing of Intronless Pre-mRNAs
PPP1CA protein phosphatase 1 catalytic subunit alpha
  • Triglyceride catabolism
  • DARPP-32 events
  • Downregulation of TGF-beta receptor signaling
  • Circadian Clock
  • 2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid
TRRAP transformation/transcription domain associated protein
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • HATs acetylate histones
  • Ub-specific processing proteases
AKAP13 A-kinase anchoring protein 13
  • NRAGE signals death through JNK
  • Rho GTPase cycle
  • G alpha (12/13) signalling events
ANGPTL4 angiopoietin like 4
  • PPARA activates gene expression
  • Transcriptional regulation of white adipocyte differentiation
  • Assembly of active LPL and LIPC lipase complexes
ARHGEF15 Rho guanine nucleotide exchange factor 15
  • NRAGE signals death through JNK
  • Rho GTPase cycle
  • G alpha (12/13) signalling events
CDC25B cell division cycle 25B
  • Cyclin A/B1/B2 associated events during G2/M transition
  • Cyclin A:Cdk2-associated events at S phase entry
  • Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
  • L-cysteic acid

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