ESR1 - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
BAP1	BRCA1 associated protein 1	UCH proteinases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
CITED1	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1	Activation of the TFAP2 (AP-2) family of transcription factors Estrogen-dependent gene expression
DARS1	aspartyl-tRNA synthetase 1	Selenoamino acid metabolism Cytosolic tRNA aminoacylation	Aspartic acid
HNRNPD	heterogeneous nuclear ribonucleoprotein D	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	Artenimol
ISL1	ISL LIM homeobox 1	Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Regulation of expression of SLITs and ROBOs
KIF1A	kinesin family member 1A	COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate Phosphoaminophosphonic Acid-Adenylate Ester
KLF5	Kruppel like factor 5	Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of granulopoiesis
KLK5	kallikrein related peptidase 5	Formation of the cornified envelope Formation of the cornified envelope
KRT10	keratin 10	Keratinization Formation of the cornified envelope	Zinc Copper Zinc acetate	Ichthyosis with confetti; Congenital reticular ichthyosiform erythroderma; Ichthyosis variegata Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE)
KRT18	keratin 18	Keratinization Formation of the cornified envelope
KRT19	keratin 19	Keratinization Formation of the cornified envelope
KRT8	keratin 8	Keratinization Formation of the cornified envelope	Tenecteplase Lanoteplase Copper
LARS1	leucyl-tRNA synthetase 1	Selenoamino acid metabolism Cytosolic tRNA aminoacylation	Leucine
LDB1	LIM domain binding 1	RUNX1 regulates transcription of genes involved in differentiation of HSCs Regulation of expression of SLITs and ROBOs
MARS1	methionyl-tRNA synthetase 1	Selenoamino acid metabolism Cytosolic tRNA aminoacylation
NR2C1	nuclear receptor subfamily 2 group C member 1	Nuclear Receptor transcription pathway SUMOylation of intracellular receptors
OTUB1	OTU deubiquitinase, ubiquitin aldehyde binding 1	Ub-specific processing proteases Ovarian tumor domain proteases
PELP1	proline, glutamate and leucine rich protein 1	Major pathway of rRNA processing in the nucleolus and cytosol PTK6 Expression
POU2F2	POU class 2 homeobox 2	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
PRPF6	pre-mRNA processing factor 6	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway

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