TOMM20 and PPHLN1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TOMM20	PPHLN1
Description		translocase of outer mitochondrial membrane 20	periphilin 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Integral Component Of Mitochondrial Outer Membrane Mitochondria-associated Endoplasmic Reticulum Membrane	Nucleoplasm Chromosome Golgi Apparatus Cytosol
	Molecular Function	Protein Binding Protein Transmembrane Transporter Activity P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity Mitochondrion Targeting Sequence Binding Unfolded Protein Binding	RNA Binding Protein Binding
	Biological Process	Protein Targeting To Mitochondrion Response To Muscle Activity TRNA Import Into Mitochondrion Macroautophagy Protein Deubiquitination Protein Import Into Mitochondrial Matrix Response To 3,3',5-triiodo-L-thyronine	Keratinization Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly Protein Localization To Heterochromatin
Pathways		Mitochondrial protein import PINK1-PRKN Mediated Mitophagy Ub-specific processing proteases
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Cholesterol, total ( 20686565) Cobalt levels ( 26025379) Immune reponse to smallpox (secreted IL-2) ( 22610502) LDL cholesterol ( 20686565) LDL cholesterol levels ( 32203549) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661)	Body size at age 10 ( 32376654) Coronary artery disease ( 29212778) Diastolic blood pressure ( 30224653) Refractive error ( 32231278)
Interacting Genes		19 interacting genes: AIP APOA1 ATXN1 BAG6 BCL2 CDC73 CEP126 DHFR FBXO7 FEZ1 HAP1 HSD17B10 OTC PPHLN1 PTN TOMM22 TOMM40 UCP1 VDAC1	25 interacting genes: APP BCL2L1 BRCA1 CASP5 CCDC57 CDC37 CDK6 CLK1 FBXO7 ITGB1BP2 MTUS2 NAGK PAXIP1 PPL SEPTIN8 SNCAIP SQSTM1 SRPK2 TGM2 TOMM20 TOPBP1 TP53BP2 TSGA10 UFD1 VIM
Entrez ID		9804	51535
HPRD ID		03507	10488
Ensembl ID		ENSG00000173726	ENSG00000134283
Uniprot IDs		A0A024R3W2 Q15388	Q8NEY8
PDB IDs		4APO	6SWG
Enriched GO Terms of Interacting Partners?
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