PPHLN1 and CASP5

Data Source:
HPRD (in vitro)

		PPHLN1	CASP5
Description		periphilin 1	caspase 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Chromosome Golgi Apparatus Cytosol	Cytoplasm NLRP1 Inflammasome Complex
	Molecular Function	RNA Binding Protein Binding	Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis
	Biological Process	Keratinization Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly Protein Localization To Heterochromatin	Proteolysis Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Substantia Nigra Development Regulation Of Apoptotic Process Regulation Of Inflammatory Response Cellular Response To Mechanical Stimulus Apoptotic Signaling Pathway Execution Phase Of Apoptosis
Pathways
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Coronary artery disease ( 29212778) Diastolic blood pressure ( 30224653) Refractive error ( 32231278)
Interacting Genes		25 interacting genes: APP BCL2L1 BRCA1 CASP5 CCDC57 CDC37 CDK6 CLK1 FBXO7 ITGB1BP2 MTUS2 NAGK PAXIP1 PPL SEPTIN8 SNCAIP SQSTM1 SRPK2 TGM2 TOMM20 TOPBP1 TP53BP2 TSGA10 UFD1 VIM	3 interacting genes: MAX NLRP1 PPHLN1
Entrez ID		51535	838
HPRD ID		10488	04048
Ensembl ID		ENSG00000134283	ENSG00000137757
Uniprot IDs		Q8NEY8	P51878
PDB IDs		6SWG
Enriched GO Terms of Interacting Partners?
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