GPRASP1 and OFD1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GPRASP1	OFD1
Description		G protein-coupled receptor associated sorting protein 1	OFD1 centriole and centriolar satellite protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Extracellular Region Nucleus Centrosome Centriole Cytosol Cilium Microtubule Cytoskeleton Membrane Motile Cilium Centriolar Satellite Ciliary Basal Body
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding
	Biological Process	Endosome To Lysosome Transport G Protein-coupled Receptor Catabolic Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Mitotic Spindle Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Hedgehog 'off' state Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases			Oral-facial-digital syndrome 1 Joubert syndrome
GWAS
Interacting Genes		47 interacting genes: ADRB1 ADRB2 AGTR1 ATXN7 C8orf33 CALCR CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRIP1 CXCR2 F2R F2RL1 GLP1R GLYAT GRM1 GRM5 GRM8 HGH1 HMOX2 HTR7 LAMTOR5 LRP2 MAP7D1 MLNR MTF2 OFD1 OPRD1 OPRK1 OPRL1 OPRM1 OXTR PBK PER1 PFDN1 SNAPIN STMN2 TAC3 TACR1 TACR2 TACR3 TBXA2R TFG TRAF4 VIPR1	8 interacting genes: CCSER2 CEP126 EIF6 GPRASP1 LUC7L2 NME7 RUVBL1 S100A6
Entrez ID		9737	8481
HPRD ID		02333	02162
Ensembl ID		ENSG00000198932	ENSG00000046651
Uniprot IDs		Q5JY77	A6NF31 E9KL37 O75665
PDB IDs
Enriched GO Terms of Interacting Partners?
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