OFD1 and S100A6

Data Source:
BioGRID (pull down)

		OFD1	S100A6
Description		OFD1 centriole and centriolar satellite protein	S100 calcium binding protein A6
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Centrosome Centriole Cytosol Cilium Microtubule Cytoskeleton Membrane Motile Cilium Centriolar Satellite Ciliary Basal Body	Ruffle Extracellular Region Nucleus Nuclear Envelope Cytoplasm Cytosol Plasma Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding	Calcium Ion Binding Protein Binding Tropomyosin Binding Zinc Ion Binding Ion Transmembrane Transporter Activity Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Mitotic Spindle Assembly Ciliary Basal Body-plasma Membrane Docking	Signal Transduction Axonogenesis Ion Transmembrane Transport Positive Regulation Of Fibroblast Proliferation
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Hedgehog 'off' state Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases		Oral-facial-digital syndrome 1 Joubert syndrome
GWAS			HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		8 interacting genes: CCSER2 CEP126 EIF6 GPRASP1 LUC7L2 NME7 RUVBL1 S100A6	17 interacting genes: ANXA11 ANXA2 CACYBP CEP20 CEP43 FAM25A FAM25C FAM25G FKBP4 GAPDH MDM2 OFD1 PEX5 PPID S100B SUGT1 TP53
Entrez ID		8481	6277
HPRD ID		02162	00237
Ensembl ID		ENSG00000046651	ENSG00000197956
Uniprot IDs		A6NF31 E9KL37 O75665	P06703
PDB IDs			1K8U 1K96 1K9K 1K9P 2M1K 4YBH
Enriched GO Terms of Interacting Partners?
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