GPRASP1 and TACR3

Data Source:
HPRD (in vitro)

		GPRASP1	TACR3
Description		G protein-coupled receptor associated sorting protein 1	tachykinin receptor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Dendrite Membrane Neuronal Cell Body Membrane Sperm Midpiece
	Molecular Function	Protein Binding	Tachykinin Receptor Activity Protein Binding
	Biological Process	Endosome To Lysosome Transport G Protein-coupled Receptor Catabolic Process	G Protein-coupled Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Aging Positive Regulation Of Heart Rate Response To Estradiol Regulation Of Dopamine Metabolic Process Response To Cocaine Hyperosmotic Salinity Response Response To Morphine Positive Regulation Of Blood Pressure Regulation Of Feeding Behavior Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Flagellated Sperm Motility
Pathways			Tachykinin receptors bind tachykinins G alpha (q) signalling events
Drugs			Osanetant Talnetant Pavinetant
Diseases			Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS			Chronotype ( 30696823) Heel bone mineral density ( 30598549) Height ( 31562340) Menarche (age at onset) ( 27182965 25231870) Rosacea symptom severity ( 29771307) Spontaneous preterm birth without premature rupture of membranes ( 31194736)
Interacting Genes		47 interacting genes: ADRB1 ADRB2 AGTR1 ATXN7 C8orf33 CALCR CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRIP1 CXCR2 F2R F2RL1 GLP1R GLYAT GRM1 GRM5 GRM8 HGH1 HMOX2 HTR7 LAMTOR5 LRP2 MAP7D1 MLNR MTF2 OFD1 OPRD1 OPRK1 OPRL1 OPRM1 OXTR PBK PER1 PFDN1 SNAPIN STMN2 TAC3 TACR1 TACR2 TACR3 TBXA2R TFG TRAF4 VIPR1	4 interacting genes: GPRASP1 TAC1 TAC3 TAC4
Entrez ID		9737	6870
HPRD ID		02333	01209
Ensembl ID		ENSG00000198932	ENSG00000169836
Uniprot IDs		Q5JY77	P29371
PDB IDs
Enriched GO Terms of Interacting Partners?
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