OFD1 and CCSER2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		OFD1	CCSER2
Description		OFD1 centriole and centriolar satellite protein	coiled-coil serine rich protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Centrosome Centriole Cytosol Cilium Microtubule Cytoskeleton Membrane Motile Cilium Centriolar Satellite Ciliary Basal Body	Cytoplasm Microtubule Cytoskeleton
	Molecular Function	Protein Binding Identical Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding	Microtubule Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Mitotic Spindle Assembly Ciliary Basal Body-plasma Membrane Docking	Microtubule Bundle Formation
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Hedgehog 'off' state Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases		Oral-facial-digital syndrome 1 Joubert syndrome
GWAS			Cerebrospinal P-tau181p levels ( 28247064) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Refractive error ( 32231278)
Interacting Genes		8 interacting genes: CCSER2 CEP126 EIF6 GPRASP1 LUC7L2 NME7 RUVBL1 S100A6	11 interacting genes: APP ATRX CRADD EXOC1 GTF2H1 KIFAP3 MAP1LC3B OFD1 PSMD11 STX1A TCEA2
Entrez ID		8481	54462
HPRD ID		02162	13832
Ensembl ID		ENSG00000046651	ENSG00000107771
Uniprot IDs		A6NF31 E9KL37 O75665	Q9H7U1
PDB IDs
Enriched GO Terms of Interacting Partners?
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