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FXR2 and PAF1
Data Source:
BioGRID
(two hybrid)
FXR2
PAF1
Description
FMR1 autosomal homolog 2
PAF1 homolog, Paf1/RNA polymerase II complex component
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Polysome
Postsynaptic Density
Membrane
Cytosolic Large Ribosomal Subunit
Axon
Growth Cone
Cytoplasmic Ribonucleoprotein Granule
Neuronal Cell Body
Dendritic Spine
Dendritic Spine Neck
Presynapse
Dendritic Filopodium
Nucleoplasm
Cytoplasm
Membrane
Cdc73/Paf1 Complex
Cell Junction
Transcriptionally Active Chromatin
Molecular Function
RNA Binding
MRNA 3'-UTR Binding
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Translation Regulator Activity
Protein Heterodimerization Activity
RNA Polymerase II Complex Binding
Chromatin Binding
Protein Binding
Biological Process
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Positive Regulation Of Protein Phosphorylation
Negative Regulation Of Translation
Regulation Of MRNA Stability
Positive Regulation Of Translation
Regulation Of Filopodium Assembly
Positive Regulation Of Response To DNA Damage Stimulus
Negative Regulation Of Transcription By RNA Polymerase II
Endodermal Cell Fate Commitment
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
MRNA Polyadenylation
Histone Monoubiquitination
Wnt Signaling Pathway
Protein Ubiquitination
Nucleosome Positioning
Stem Cell Population Maintenance
Positive Regulation Of Histone Methylation
Positive Regulation Of MRNA 3'-end Processing
Histone H2B Ubiquitination
Protein Localization To Nucleus
Negative Regulation Of Myeloid Cell Differentiation
Cellular Response To Lipopolysaccharide
Positive Regulation Of Cell Cycle G1/S Phase Transition
Pathways
Formation of RNA Pol II elongation complex
RNA Polymerase II Pre-transcription Events
RNA Polymerase II Transcription Elongation
E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Atrial fibrillation (
30061737
)
Brain morphology (MOSTest) (
32665545
)
IgM levels (
23118916
)
Refractive error (
32231278
)
Sex hormone-binding globulin levels (
22675492
)
Interacting Genes
107 interacting genes:
AKAP9
AMOTL2
AP1M1
AP2M1
ARL6IP1
BAZ2B
BLK
BRCA1
BYSL
C10orf62
C1orf35
CALCOCO2
CBS
CCDC33
CCDC85B
CCR4
CDKL3
CEP44
CEP55
COIL
CWF19L2
CYFIP1
CYFIP2
DDX17
DMRTB1
DPPA2
DYNLT1
EIF4G1
EWSR1
FAM90A1
FBP1
FMR1
FTH1
FXR1
GKAP1
GTSE1
HMBOX1
HNRNPC
IGFN1
INPP5J
KCNRG
KCTD4
KIAA1217
KIF1A
KIF2A
KRT20
KXD1
LASP1
LCMT1
LCP2
LDOC1
MAPRE3
MBIP
MCRS1
MEAF6
MFAP1
MIA3
MORF4L1
MRPL43
NCK2
NDEL1
NDN
NECAB2
NEXN
NIF3L1
NME1
NONO
NT5C2
PAF1
PAICS
PCBD1
PCM1
PIM1
POM121
PRAM1
PRC1
PSME3
PTS
RABAC1
RALYL
RBBP8
RBM14
RBMX
RBPMS
RPIA
RTN3
RTN4
SCEL
SNAP23
SYT6
SYTL4
TBC1D22B
THAP1
TNNT1
TRAF2
TRIM23
TRIM29
TRIM37
TSC22D4
YES1
ZBTB22
ZBTB8A
ZMAT2
ZNF232
ZNF451
ZNRD2
ZSCAN1
17 interacting genes:
ENO1
ERCC6
FXR2
H1-2
H3C1
HSPB1
KAT8
KMT2A
LEO1
MLLT1
MSL1
MSL2
MSL3
RNF20
SUMO2
TCEA1
TULP3
Entrez ID
9513
54623
HPRD ID
05629
10140
Ensembl ID
ENSG00000129245
ENSG00000006712
Uniprot IDs
P51116
A0A024R0H6
Q8N7H5
PDB IDs
3H8Z
4M6T
5ZYQ
6GMH
6TED
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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