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FXR2 and PRC1
Data Source:
BioGRID
(two hybrid, affinity chromatography technology)
FXR2
PRC1
Description
FMR1 autosomal homolog 2
protein regulator of cytokinesis 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Polysome
Postsynaptic Density
Membrane
Cytosolic Large Ribosomal Subunit
Axon
Growth Cone
Cytoplasmic Ribonucleoprotein Granule
Neuronal Cell Body
Dendritic Spine
Dendritic Spine Neck
Presynapse
Dendritic Filopodium
Spindle Pole
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Spindle
Cytosol
Spindle Microtubule
Plasma Membrane
Microtubule Cytoskeleton
Midbody
Intercellular Bridge
Contractile Ring
Mitotic Spindle Midzone
Molecular Function
RNA Binding
MRNA 3'-UTR Binding
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Translation Regulator Activity
Protein Heterodimerization Activity
Protein Binding
Microtubule Binding
Kinesin Binding
Protein Kinase Binding
Biological Process
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Positive Regulation Of Protein Phosphorylation
Negative Regulation Of Translation
Regulation Of MRNA Stability
Positive Regulation Of Translation
Regulation Of Filopodium Assembly
Positive Regulation Of Response To DNA Damage Stimulus
Mitotic Spindle Elongation
Microtubule Cytoskeleton Organization
Microtubule Bundle Formation
Positive Regulation Of Cell Population Proliferation
Regulation Of Cytokinesis
Mitotic Spindle Midzone Assembly
Cell Division
Pathways
RHO GTPases activate CIT
Drugs
Diseases
GWAS
Atrial fibrillation (
30061737
)
Brain morphology (MOSTest) (
32665545
)
IgM levels (
23118916
)
Refractive error (
32231278
)
Sex hormone-binding globulin levels (
22675492
)
Breast cancer (
29059683
25038754
)
Mean platelet volume (
32888494
27863252
)
Multisite chronic pain (
31194737
)
Red cell distribution width (
32888494
)
Type 2 diabetes (
22885922
24509480
30054458
30297969
26818947
32499647
20581827
30718926
28869590
)
Interacting Genes
107 interacting genes:
AKAP9
AMOTL2
AP1M1
AP2M1
ARL6IP1
BAZ2B
BLK
BRCA1
BYSL
C10orf62
C1orf35
CALCOCO2
CBS
CCDC33
CCDC85B
CCR4
CDKL3
CEP44
CEP55
COIL
CWF19L2
CYFIP1
CYFIP2
DDX17
DMRTB1
DPPA2
DYNLT1
EIF4G1
EWSR1
FAM90A1
FBP1
FMR1
FTH1
FXR1
GKAP1
GTSE1
HMBOX1
HNRNPC
IGFN1
INPP5J
KCNRG
KCTD4
KIAA1217
KIF1A
KIF2A
KRT20
KXD1
LASP1
LCMT1
LCP2
LDOC1
MAPRE3
MBIP
MCRS1
MEAF6
MFAP1
MIA3
MORF4L1
MRPL43
NCK2
NDEL1
NDN
NECAB2
NEXN
NIF3L1
NME1
NONO
NT5C2
PAF1
PAICS
PCBD1
PCM1
PIM1
POM121
PRAM1
PRC1
PSME3
PTS
RABAC1
RALYL
RBBP8
RBM14
RBMX
RBPMS
RPIA
RTN3
RTN4
SCEL
SNAP23
SYT6
SYTL4
TBC1D22B
THAP1
TNNT1
TRAF2
TRIM23
TRIM29
TRIM37
TSC22D4
YES1
ZBTB22
ZBTB8A
ZMAT2
ZNF232
ZNF451
ZNRD2
ZSCAN1
29 interacting genes:
AKAP9
CASK
CCDC85B
CCNA2
CCNB1
CCNE1
CDK1
CDK2
CINP
FXR2
KIF3B
KIF4A
KLC2
KLC4
KRT20
MAT2A
NDEL1
PCM1
PKIA
PLK1
RACGAP1
RBM10
RPA2
SF3B2
SLAIN1
SUMO2
TRIM37
USHBP1
YWHAE
Entrez ID
9513
9055
HPRD ID
05629
17899
Ensembl ID
ENSG00000129245
ENSG00000198901
Uniprot IDs
P51116
A0A024RC67
O43663
PDB IDs
3H8Z
3NRX
3NRY
4L3I
4L6Y
5KMG
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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