FXR2 and GTSE1

Data Source:
BioGRID (two hybrid)

		FXR2	GTSE1
Description		FMR1 autosomal homolog 2	G2 and S-phase expressed 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Polysome Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Axon Growth Cone Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Dendritic Spine Dendritic Spine Neck Presynapse Dendritic Filopodium	Nucleoplasm Cytosol Cytoplasmic Microtubule Microtubule Cytoskeleton Membrane
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Translation Regulator Activity Protein Heterodimerization Activity	Molecular_function Protein Binding Microtubule Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Phosphorylation Negative Regulation Of Translation Regulation Of MRNA Stability Positive Regulation Of Translation Regulation Of Filopodium Assembly Positive Regulation Of Response To DNA Damage Stimulus	DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Microtubule-based Process Positive Regulation Of Cell Migration Positive Regulation Of Protein Export From Nucleus Protein Stabilization Positive Regulation Of Protein Localization To Nucleus Regulation Of Cell Cycle G2/M Phase Transition
Pathways			G2/M Checkpoints The role of GTSE1 in G2/M progression after G2 checkpoint
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737) Brain morphology (MOSTest) ( 32665545) IgM levels ( 23118916) Refractive error ( 32231278) Sex hormone-binding globulin levels ( 22675492)
Interacting Genes		107 interacting genes: AKAP9 AMOTL2 AP1M1 AP2M1 ARL6IP1 BAZ2B BLK BRCA1 BYSL C10orf62 C1orf35 CALCOCO2 CBS CCDC33 CCDC85B CCR4 CDKL3 CEP44 CEP55 COIL CWF19L2 CYFIP1 CYFIP2 DDX17 DMRTB1 DPPA2 DYNLT1 EIF4G1 EWSR1 FAM90A1 FBP1 FMR1 FTH1 FXR1 GKAP1 GTSE1 HMBOX1 HNRNPC IGFN1 INPP5J KCNRG KCTD4 KIAA1217 KIF1A KIF2A KRT20 KXD1 LASP1 LCMT1 LCP2 LDOC1 MAPRE3 MBIP MCRS1 MEAF6 MFAP1 MIA3 MORF4L1 MRPL43 NCK2 NDEL1 NDN NECAB2 NEXN NIF3L1 NME1 NONO NT5C2 PAF1 PAICS PCBD1 PCM1 PIM1 POM121 PRAM1 PRC1 PSME3 PTS RABAC1 RALYL RBBP8 RBM14 RBMX RBPMS RPIA RTN3 RTN4 SCEL SNAP23 SYT6 SYTL4 TBC1D22B THAP1 TNNT1 TRAF2 TRIM23 TRIM29 TRIM37 TSC22D4 YES1 ZBTB22 ZBTB8A ZMAT2 ZNF232 ZNF451 ZNRD2 ZSCAN1	10 interacting genes: AKAP9 CASK FXR2 HNRNPD KIFAP3 MAPRE1 MAPRE2 MAPRE3 NIN RBM10
Entrez ID		9513	51512
HPRD ID		05629	09593
Ensembl ID		ENSG00000129245	ENSG00000075218
Uniprot IDs		P51116	Q9NYZ3
PDB IDs		3H8Z	6QNN 6QNP
Enriched GO Terms of Interacting Partners?
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