ECEL1 and USP19

Data Source:
BioGRID (two hybrid)

		ECEL1	USP19
Description		endothelin converting enzyme like 1	ubiquitin specific peptidase 19
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane
	Molecular Function	Metalloendopeptidase Activity Metallopeptidase Activity Metal Ion Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Ubiquitin Protein Ligase Binding Metal Ion Binding Hsp90 Protein Binding Lys48-specific Deubiquitinase Activity
	Biological Process	Respiratory System Process Neuropeptide Signaling Pathway Protein Processing	Protein Deubiquitination Protein Phosphopantetheinylation Ubiquitin-dependent ERAD Pathway Regulation Of Protein Stability Response To Endoplasmic Reticulum Stress Negative Regulation Of Skeletal Muscle Tissue Development Protein Stabilization Protein K48-linked Deubiquitination Positive Regulation Of Cell Cycle Process Regulation Of Cellular Response To Hypoxia Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of ERAD Pathway
Pathways			Ub-specific processing proteases
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		1 interacting genes: USP19	13 interacting genes: BIRC3 CKAP5 ECEL1 FLNA HIF1A HNRNPAB HSP90AA1 LAMTOR4 RNF2 SIAH1 SIAH2 SNRNP200 UBC
Entrez ID		9427	10869
HPRD ID		07066	18278
Ensembl ID		ENSG00000171551	ENSG00000172046
Uniprot IDs		A0A6F7YIA8 O95672	O94966
PDB IDs			1WH0 4X3G 6K7W 6KHV 6KQV
Enriched GO Terms of Interacting Partners?
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