USP19 and HNRNPAB

Data Source:
BioGRID (two hybrid)

		USP19	HNRNPAB
Description		ubiquitin specific peptidase 19	heterogeneous nuclear ribonucleoprotein A/B
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane	Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Regulator Complex Ribonucleoprotein Complex
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Ubiquitin Protein Ligase Binding Metal Ion Binding Hsp90 Protein Binding Lys48-specific Deubiquitinase Activity	RNA Binding MRNA Binding Protein Binding
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation Ubiquitin-dependent ERAD Pathway Regulation Of Protein Stability Response To Endoplasmic Reticulum Stress Negative Regulation Of Skeletal Muscle Tissue Development Protein Stabilization Protein K48-linked Deubiquitination Positive Regulation Of Cell Cycle Process Regulation Of Cellular Response To Hypoxia Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of ERAD Pathway	Epithelial To Mesenchymal Transition Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated
Pathways		Ub-specific processing proteases
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Blood protein levels ( 30072576) Immature fraction of reticulocytes ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		13 interacting genes: BIRC3 CKAP5 ECEL1 FLNA HIF1A HNRNPAB HSP90AA1 LAMTOR4 RNF2 SIAH1 SIAH2 SNRNP200 UBC	19 interacting genes: ACTB CDC42 DEDD2 ELAVL2 ERG H3-4 H3C1 HMGA1 HOXC13 HOXD4 IL7R POLR3D PTBP1 PTBP2 PTEN RBFOX2 TP63 USP19 YWHAG
Entrez ID		10869	3182
HPRD ID		18278	04067
Ensembl ID		ENSG00000172046	ENSG00000197451
Uniprot IDs		O94966	Q99729
PDB IDs		1WH0 4X3G 6K7W 6KHV 6KQV	3S7R
Enriched GO Terms of Interacting Partners?
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