USP19 and ECEL1

Data Source:
BioGRID (two hybrid)

		USP19	ECEL1
Description		ubiquitin specific peptidase 19	endothelin converting enzyme like 1
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Ubiquitin Protein Ligase Binding Metal Ion Binding Hsp90 Protein Binding Lys48-specific Deubiquitinase Activity	Metalloendopeptidase Activity Metallopeptidase Activity Metal Ion Binding
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation Ubiquitin-dependent ERAD Pathway Regulation Of Protein Stability Response To Endoplasmic Reticulum Stress Negative Regulation Of Skeletal Muscle Tissue Development Protein Stabilization Protein K48-linked Deubiquitination Positive Regulation Of Cell Cycle Process Regulation Of Cellular Response To Hypoxia Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of ERAD Pathway	Respiratory System Process Neuropeptide Signaling Pathway Protein Processing
Pathways		Ub-specific processing proteases
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Refractive error ( 32231278)
Interacting Genes		13 interacting genes: BIRC3 CKAP5 ECEL1 FLNA HIF1A HNRNPAB HSP90AA1 LAMTOR4 RNF2 SIAH1 SIAH2 SNRNP200 UBC	1 interacting genes: USP19
Entrez ID		10869	9427
HPRD ID		18278	07066
Ensembl ID		ENSG00000172046	ENSG00000171551
Uniprot IDs		O94966	A0A6F7YIA8 O95672
PDB IDs		1WH0 4X3G 6K7W 6KHV 6KQV
Enriched GO Terms of Interacting Partners?
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