GRAP2 and KHDRBS2

Data Source:
BioGRID (two hybrid)

		GRAP2	KHDRBS2
Description		GRB2 related adaptor protein 2	KH RNA binding domain containing, signal transduction associated 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Plasma Membrane	Nucleus Nucleoplasm
	Molecular Function	Protein Binding	MRNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding
	Biological Process	Ras Protein Signal Transduction Cell-cell Signaling T Cell Costimulation Fc-epsilon Receptor Signaling Pathway T Cell Receptor Signaling Pathway	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Signaling by SCF-KIT Generation of second messenger molecules DAP12 signaling FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization CD28 co-stimulation FLT3 Signaling	PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS		Body mass index ( 26426971) Systemic lupus erythematosus ( 28714469)	Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Chronotype ( 30696823) Corneal astigmatism ( 30306274) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Esophageal adenocarcinoma ( 27527254) Presence of antiphospholipid antibodies ( 27098658) Protein quantitative trait loci ( 18464913)
Interacting Genes		79 interacting genes: AR BAG4 BEND5 BLNK CBL CBLB CBY2 CCHCR1 CCNDBP1 CD28 COG6 CSF1R DNM2 DVL2 EGFR ERBB2 ERBB3 ERBB4 ETV5 FASLG GAB1 GAB2 GAB3 GAREM1 GATA1 GFAP GOLGA2 GRB2 HNRNPK IHO1 IKZF3 KHDRBS1 KHDRBS2 KIT KPRP KRT13 KRTAP1-3 KRTAP4-11 KRTAP4-12 LAT LATS2 LAX1 LCP2 LNX1 LNX2 MAGED1 MAP4K1 MKRN3 MOS MTUS2 PBLD PNMA1 PRKAA2 PRPH2 PRR35 RACK1 RAVER1 RBPMS RIN3 RINT1 SH2D4A SHB SHC1 SOS2 SPRY2 SSX2IP STAMBP TFIP11 TLE5 TRAF1 TSNAXIP1 USP8 WWP2 YWHAE ZBTB7B ZNF250 ZNF319 ZNF526 ZSCAN21	47 interacting genes: AEN BAHD1 BMP7 CATSPER1 CHTOP CIRBP CNNM3 DALRD3 DOCK2 EWSR1 FOXD4L3 GRAP2 GRB2 HBZ HHEX HNRNPK HNRNPLL KHDRBS3 LINC01018 LMNTD2 LNX1 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PSMF1 PTK6 RBM10 RBM14 RBM3 RBMX RFC3 SDCBP SPG7 SULT1A3 TMEM14B TYK2 TYMSOS YTHDC1 ZFC3H1 ZNF497 ZNF581 ZNF688 ZNF837
Entrez ID		9402	202559
HPRD ID		05156	13775
Ensembl ID		ENSG00000100351	ENSG00000112232
Uniprot IDs		B7Z8E3 O75791 Q6FI14	A0A6Q8PGH5 Q5VWX1
PDB IDs		5GJH
Enriched GO Terms of Interacting Partners?
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