GRAP2 and RAVER1

Data Source:
BioGRID (two hybrid)

		GRAP2	RAVER1
Description		GRB2 related adaptor protein 2	ribonucleoprotein, PTB binding 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Plasma Membrane	Nucleus Cytoplasm
	Molecular Function	Protein Binding	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Ras Protein Signal Transduction Cell-cell Signaling T Cell Costimulation Fc-epsilon Receptor Signaling Pathway T Cell Receptor Signaling Pathway	MRNA Splicing, Via Spliceosome
Pathways		Signaling by SCF-KIT Generation of second messenger molecules DAP12 signaling FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization CD28 co-stimulation FLT3 Signaling
Drugs
Diseases
GWAS		Body mass index ( 26426971) Systemic lupus erythematosus ( 28714469)	Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Plateletcrit ( 27863252) Rheumatoid arthritis ( 30572963 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Type 1 diabetes ( 30572963)
Interacting Genes		79 interacting genes: AR BAG4 BEND5 BLNK CBL CBLB CBY2 CCHCR1 CCNDBP1 CD28 COG6 CSF1R DNM2 DVL2 EGFR ERBB2 ERBB3 ERBB4 ETV5 FASLG GAB1 GAB2 GAB3 GAREM1 GATA1 GFAP GOLGA2 GRB2 HNRNPK IHO1 IKZF3 KHDRBS1 KHDRBS2 KIT KPRP KRT13 KRTAP1-3 KRTAP4-11 KRTAP4-12 LAT LATS2 LAX1 LCP2 LNX1 LNX2 MAGED1 MAP4K1 MKRN3 MOS MTUS2 PBLD PNMA1 PRKAA2 PRPH2 PRR35 RACK1 RAVER1 RBPMS RIN3 RINT1 SH2D4A SHB SHC1 SOS2 SPRY2 SSX2IP STAMBP TFIP11 TLE5 TRAF1 TSNAXIP1 USP8 WWP2 YWHAE ZBTB7B ZNF250 ZNF319 ZNF526 ZSCAN21	5 interacting genes: ACTN1 ACTN2 GRAP2 PTBP1 VCL
Entrez ID		9402	125950
HPRD ID		05156	11484
Ensembl ID		ENSG00000100351	ENSG00000161847
Uniprot IDs		B7Z8E3 O75791 Q6FI14	E9PAU2 Q8IY67
PDB IDs		5GJH	3H2U 3H2V 3SMZ 3VF0
Enriched GO Terms of Interacting Partners?
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