KHDRBS2 and NCOA5

Data Source:
BioGRID (two hybrid)

		KHDRBS2	NCOA5
Description		KH RNA binding domain containing, signal transduction associated 2	nuclear receptor coactivator 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Extracellular Space Nucleoplasm Actin Cytoskeleton
	Molecular Function	MRNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding	Chromatin Binding Transcription Corepressor Activity RNA Binding Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome	Negative Regulation Of Transcription By RNA Polymerase II Glucose Homeostasis Negative Regulation Of Insulin Receptor Signaling Pathway
Pathways		PTK6 Regulates Proteins Involved in RNA Processing
Drugs			17alpha-Estriol
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Chronotype ( 30696823) Corneal astigmatism ( 30306274) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Esophageal adenocarcinoma ( 27527254) Presence of antiphospholipid antibodies ( 27098658) Protein quantitative trait loci ( 18464913)	Crohn's disease ( 28067908) Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831) Follicular lymphoma or multiple sclerosis ( 31407831) HDL cholesterol levels ( 32203549) Hodgkin's lymphoma ( 30194254) Inflammatory bowel disease ( 28067908) Marginal zone lymphoma or multiple sclerosis ( 31407831) Multiple sclerosis ( 31604244 21833088) Systemic lupus erythematosus ( 28714469) Tonsillectomy ( 27182965 28928442)
Interacting Genes		47 interacting genes: AEN BAHD1 BMP7 CATSPER1 CHTOP CIRBP CNNM3 DALRD3 DOCK2 EWSR1 FOXD4L3 GRAP2 GRB2 HBZ HHEX HNRNPK HNRNPLL KHDRBS3 LINC01018 LMNTD2 LNX1 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PSMF1 PTK6 RBM10 RBM14 RBM3 RBMX RFC3 SDCBP SPG7 SULT1A3 TMEM14B TYK2 TYMSOS YTHDC1 ZFC3H1 ZNF497 ZNF581 ZNF688 ZNF837	19 interacting genes: ACOT7 CCDC57 CDC37 FAM214B GORASP2 HTATIP2 KANK2 KHDRBS2 KHDRBS3 MEIG1 NR1D2 NTAQ1 PICK1 RAB30 SYT16 TSC22D1 TSGA10IP UBL5 ZNF326
Entrez ID		202559	57727
HPRD ID		13775	14813
Ensembl ID		ENSG00000112232	ENSG00000124160
Uniprot IDs		A0A6Q8PGH5 Q5VWX1	Q9HCD5
PDB IDs			1V95 2J7X 2J7Y 4ZI1
Enriched GO Terms of Interacting Partners?
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