MS4A3 and SMCO4

Data Source:
BioGRID (two hybrid)

		MS4A3	SMCO4
Description		membrane spanning 4-domains A3	single-pass membrane protein with coiled-coil domains 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Perinuclear Region Of Cytoplasm	Cellular_component Integral Component Of Membrane
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process	Neutrophil Degranulation Regulation Of Cell Cycle	Biological_process
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Alzheimer's disease ( 24755620) Vitamin B12 levels ( 22367966)	Adult body size ( 32376654) Insulin levels in response to oral glucose tolerance test (30 minutes) ( 29093273)
Interacting Genes		38 interacting genes: ADIPOQ ATP6V0B BMP10 BNIP3 C4orf3 CCDC167 CD53 CD72 CDKN3 CLDN1 CLDN6 EFNA5 EMP3 ERG28 IFITM3 IGFBP5 MS4A13 NKG7 PLP1 PLPP6 SEC22A SGTA SLC22A14 SLC5A4 SMCO4 SMIM3 STX8 TEX264 TM4SF18 TMBIM6 TMEM107 TMEM140 TMEM182 TMEM218 TMEM239 VKORC1L1 YIPF6 ZFPL1	59 interacting genes: AQP6 BNIP3L CD79A CLEC10A CLTRN CPLX4 CREB3L1 CXCR2 EBP ERGIC3 FAM174A FAM209A FAM210B FFAR2 GJA8 GKN1 GPA33 GPR152 GPR42 HHLA2 ICAM3 IL10RA KASH5 KCNK5 KIR3DL1 KRT40 KRTAP10-3 KRTAP10-7 LEPROTL1 LMNA LRRC25 M6PR MGST3 MS4A3 MUC1 PEX12 PLD3 PTGES RETREG3 SCN3B SLC16A2 SLC18A1 SLC35C2 SLC41A3 SLC7A1 SLC7A14 SMIM3 SPINT1 STOM SUSD3 SYNE4 SYNPR TEX29 TFEC TMEM139 TMEM80 TMX2 VSIR WBP1
Entrez ID		932	56935
HPRD ID		09403	17008
Ensembl ID		ENSG00000149516	ENSG00000166002
Uniprot IDs		Q96HJ5	A0A024R3A3 Q9NRQ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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