RRP9 and RAP2A

Data Source:
BioGRID (two hybrid)

		RRP9	RAP2A
Description		ribosomal RNA processing 9, U3 small nucleolar RNA binding protein	RAP2A, member of RAS oncogene family
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Box C/D RNP Complex Small-subunit Processome	Cytosol Plasma Membrane Midbody Recycling Endosome Recycling Endosome Membrane
	Molecular Function	RNA Binding Protein Binding SnoRNA Binding U3 SnoRNA Binding	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	RRNA Processing	Positive Regulation Of Protein Phosphorylation Microvillus Assembly Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Cellular Protein Localization Cellular Response To Drug Establishment Of Protein Localization Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs			Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS			Gut microbiota (bacterial taxa) ( 27723756) Peripheral artery disease ( 26488411)
Interacting Genes		4 interacting genes: CSNK2A1 RAP2A SIRT7 SMURF1	32 interacting genes: ACVR1 AFDN ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 NEDD4 PLG RAF1 RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGL1 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK
Entrez ID		9136	5911
HPRD ID		08827	01547
Ensembl ID		ENSG00000114767	ENSG00000125249
Uniprot IDs		O43818	P10114
PDB IDs		4J0W 4JXM	1KAO 2RAP 3RAP
Enriched GO Terms of Interacting Partners?
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