RAP2A and FKBP2

Data Source:
BioGRID (two hybrid)

		RAP2A	FKBP2
Description		RAP2A, member of RAS oncogene family	FKBP prolyl isomerase 2
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Midbody Recycling Endosome Recycling Endosome Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane
	Molecular Function	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding GDP Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Microvillus Assembly Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Cellular Protein Localization Cellular Response To Drug Establishment Of Protein Localization Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane	Protein Peptidyl-prolyl Isomerization
Pathways
Drugs		Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756) Peripheral artery disease ( 26488411)	Crohn's disease ( 28067908) Fruit consumption ( 32066663)
Interacting Genes		32 interacting genes: ACVR1 AFDN ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 NEDD4 PLG RAF1 RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGL1 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK	14 interacting genes: ARFGEF1 BAG6 BARD1 C1QC EPB41 EPB41L2 MAPK3 RAB3C RAB6A RAP2A UBQLN1 UBQLN2 UBQLN4 VAMP2
Entrez ID		5911	2286
HPRD ID		01547	01742
Ensembl ID		ENSG00000125249	ENSG00000173486
Uniprot IDs		P10114	P26885 Q53XJ5
PDB IDs		1KAO 2RAP 3RAP	2PBC 4NNR
Enriched GO Terms of Interacting Partners?
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