RAP2A and RUNDC3A

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		RAP2A	RUNDC3A
Description		RAP2A, member of RAS oncogene family	RUN domain containing 3A
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Midbody Recycling Endosome Recycling Endosome Membrane	Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding GDP Binding	Protein Binding GTPase Regulator Activity
	Biological Process	Positive Regulation Of Protein Phosphorylation Microvillus Assembly Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Cellular Protein Localization Cellular Response To Drug Establishment Of Protein Localization Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane	Small GTPase Mediated Signal Transduction Positive Regulation Of CGMP-mediated Signaling Regulation Of Catalytic Activity
Pathways
Drugs		Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756) Peripheral artery disease ( 26488411)
Interacting Genes		32 interacting genes: ACVR1 AFDN ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 NEDD4 PLG RAF1 RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGL1 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK	35 interacting genes: AP1M1 AP2M1 ARMC7 CCNL2 DDX6 EIF3E ENKD1 FAM161A GEM GFI1B HTR6 LNX1 MAGEB4 MAGOHB MBD3L2 MRPL15 MYO15B PRPF31 RAP1A RAP2A RAP2B SDCBP SYT17 TBRG1 TEAD4 TFPT TSGA10IP TSHR UBTFL1 USP2 ZNF250 ZNF417 ZNF587 ZNF821 ZNF835
Entrez ID		5911	10900
HPRD ID		01547	16106
Ensembl ID		ENSG00000125249	ENSG00000108309
Uniprot IDs		P10114	Q59EK9
PDB IDs		1KAO 2RAP 3RAP
Enriched GO Terms of Interacting Partners?
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