DERL3 and GPR101

Data Source:
BioGRID (two hybrid)

		DERL3	GPR101
Description		derlin 3	G protein-coupled receptor 101
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase ERAD-L Complex Integral Component Of Endoplasmic Reticulum Membrane	Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Signal Recognition Particle Binding Protein Binding Protein-containing Complex Binding Misfolded Protein Binding Ubiquitin-specific Protease Binding	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Protein N-linked Glycosylation Via Asparagine Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Pathways		ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis
Drugs
Diseases
GWAS		Ejection fraction ( 29403010) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Left ventricular internal dimension in systole ( 29403010) PR interval ( 32439900) S-phenylmercapturic acid levels in smokers ( 26959369)	Body mass index ( 28892062)
Interacting Genes		19 interacting genes: EHHADH GAD2 GNLY GPR101 IL27RA MELTF NDRG4 PSCA RTP4 SDCBP SERPINA1 SLC13A4 STATH SYT16 TEX29 TMEM179B TMEM31 TMEM92 ULBP2	20 interacting genes: AGPAT4 C1GALT1 CDIPT CYB561A3 DERL3 LAT MFSD5 NDUFB11 ORMDL3 RTP2 SLC35E4 SLC39A9 SLC41A1 THSD7B TM4SF4 TMEM147 TMEM239 UNC93A UNC93B1 YIPF6
Entrez ID		91319	83550
HPRD ID		13139	02315
Ensembl ID		ENSG00000099958	ENSG00000165370
Uniprot IDs		Q96Q80	Q96P66
PDB IDs
Enriched GO Terms of Interacting Partners?
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