DERL3 and STATH

Data Source:
BioGRID (two hybrid)

		DERL3	STATH
Description		derlin 3	statherin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase ERAD-L Complex Integral Component Of Endoplasmic Reticulum Membrane	Extracellular Region
	Molecular Function	Signal Recognition Particle Binding Protein Binding Protein-containing Complex Binding Misfolded Protein Binding Ubiquitin-specific Protease Binding	Protein Binding Extracellular Matrix Constituent, Lubricant Activity Structural Constituent Of Tooth Enamel Hydroxyapatite Binding
	Biological Process	Protein N-linked Glycosylation Via Asparagine Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Ossification Negative Regulation Of Bone Mineralization Biomineral Tissue Development Defense Response To Bacterium Saliva Secretion
Pathways		ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis
Drugs
Diseases
GWAS		Ejection fraction ( 29403010) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Left ventricular internal dimension in systole ( 29403010) PR interval ( 32439900) S-phenylmercapturic acid levels in smokers ( 26959369)
Interacting Genes		19 interacting genes: EHHADH GAD2 GNLY GPR101 IL27RA MELTF NDRG4 PSCA RTP4 SDCBP SERPINA1 SLC13A4 STATH SYT16 TEX29 TMEM179B TMEM31 TMEM92 ULBP2	25 interacting genes: AQP6 C16orf92 DERL3 ERGIC3 FAM209A FCRL3 GET3 GPR152 GPR42 KCNJ6 LEUTX MFSD5 MRM1 MTIF3 OPRPN OVGP1 REEP4 SGPL1 SLC10A6 SLC39A2 SPNS3 TFAM TLCD4 TMEM80 TMX2
Entrez ID		91319	6779
HPRD ID		13139	01696
Ensembl ID		ENSG00000099958	ENSG00000126549
Uniprot IDs		Q96Q80	P02808
PDB IDs
Enriched GO Terms of Interacting Partners?
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