LRSAM1 and FAM178B

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LRSAM1	FAM178B
Description		leucine rich repeat and sterile alpha motif containing 1	family with sequence similarity 178 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Autophagy Protein Catabolic Process Negative Regulation Of Endocytosis Viral Budding Protein Autoubiquitination Ubiquitin-dependent Endocytosis Positive Regulation Of Xenophagy Positive Regulation Of Autophagosome Assembly
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494)	Bipolar disorder lithium response (continuous) or schizophrenia ( 29121268) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference ( 28552196)
Interacting Genes		42 interacting genes: ATXN1 ATXN7 CCDC6 DMAP1 FAM178B GABARAPL2 GPR108 GRIK5 GSK3A KLC1 MAGEA1 MDM4 MGAT4B MKRN3 MUTYH MYL2 NINL PHF23 RNF111 RXRG TERF1 TNFRSF10C TRIM17 TRIM74 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2H UBE2I UBE2J1 UBE2K UBE2N UBE2W UEVLD USP2 USP21 VPS11 XAF1 ZMAT4	1 interacting genes: LRSAM1
Entrez ID		90678	51252
HPRD ID		14325	14235
Ensembl ID		ENSG00000148356	ENSG00000168754
Uniprot IDs		A0A024R870 Q6UWE0	B3KV66 Q8IXR5
PDB IDs
Enriched GO Terms of Interacting Partners?
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