FAM178B and LRSAM1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FAM178B	LRSAM1
Description		family with sequence similarity 178 member B	leucine rich repeat and sterile alpha motif containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Membrane
	Molecular Function		Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process		Protein Polyubiquitination Autophagy Protein Catabolic Process Negative Regulation Of Endocytosis Viral Budding Protein Autoubiquitination Ubiquitin-dependent Endocytosis Positive Regulation Of Xenophagy Positive Regulation Of Autophagosome Assembly
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Bipolar disorder lithium response (continuous) or schizophrenia ( 29121268) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference ( 28552196)	Mean corpuscular volume ( 32888494)
Interacting Genes		1 interacting genes: LRSAM1	42 interacting genes: ATXN1 ATXN7 CCDC6 DMAP1 FAM178B GABARAPL2 GPR108 GRIK5 GSK3A KLC1 MAGEA1 MDM4 MGAT4B MKRN3 MUTYH MYL2 NINL PHF23 RNF111 RXRG TERF1 TNFRSF10C TRIM17 TRIM74 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2H UBE2I UBE2J1 UBE2K UBE2N UBE2W UEVLD USP2 USP21 VPS11 XAF1 ZMAT4
Entrez ID		51252	90678
HPRD ID		14235	14325
Ensembl ID		ENSG00000168754	ENSG00000148356
Uniprot IDs		B3KV66 Q8IXR5	A0A024R870 Q6UWE0
PDB IDs
Enriched GO Terms of Interacting Partners?
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