LRSAM1 and XAF1

Data Source:
BioGRID (two hybrid)

		LRSAM1	XAF1
Description		leucine rich repeat and sterile alpha motif containing 1	XIAP associated factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane	Nucleoplasm Mitochondrion Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Zinc Ion Binding
	Biological Process	Protein Polyubiquitination Autophagy Protein Catabolic Process Negative Regulation Of Endocytosis Viral Budding Protein Autoubiquitination Ubiquitin-dependent Endocytosis Positive Regulation Of Xenophagy Positive Regulation Of Autophagosome Assembly	Apoptotic Process Response To Interferon-beta Type I Interferon Signaling Pathway
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494)
Interacting Genes		42 interacting genes: ATXN1 ATXN7 CCDC6 DMAP1 FAM178B GABARAPL2 GPR108 GRIK5 GSK3A KLC1 MAGEA1 MDM4 MGAT4B MKRN3 MUTYH MYL2 NINL PHF23 RNF111 RXRG TERF1 TNFRSF10C TRIM17 TRIM74 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2H UBE2I UBE2J1 UBE2K UBE2N UBE2W UEVLD USP2 USP21 VPS11 XAF1 ZMAT4	18 interacting genes: AKT1 APP BIRC7 CREBBP GLS2 LRSAM1 RFC5 RNF114 RNF166 SEPHS1 TP53 TRIM21 TRIM50 TRIM54 TRIML2 UBXN2B VCP XIAP
Entrez ID		90678	54739
HPRD ID		14325	06978
Ensembl ID		ENSG00000148356	ENSG00000132530
Uniprot IDs		A0A024R870 Q6UWE0	Q6GPH4
PDB IDs			2LXW
Enriched GO Terms of Interacting Partners?
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