LRSAM1 and TRIM17

Data Source:
BioGRID (two hybrid)

		LRSAM1	TRIM17
Description		leucine rich repeat and sterile alpha motif containing 1	tripartite motif containing 17
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane	Cellular_component Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein-macromolecule Adaptor Activity Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Autophagy Protein Catabolic Process Negative Regulation Of Endocytosis Viral Budding Protein Autoubiquitination Ubiquitin-dependent Endocytosis Positive Regulation Of Xenophagy Positive Regulation Of Autophagosome Assembly	Autophagy Regulation Of Gene Expression Protein Ubiquitination Regulation Of Protein Localization Innate Immune Response Protein Autoubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Interferon gamma signaling
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494)	Non-Richardson's syndrome vs Richardson's syndrome in progressive supranuclear palsy ( 30066433)
Interacting Genes		42 interacting genes: ATXN1 ATXN7 CCDC6 DMAP1 FAM178B GABARAPL2 GPR108 GRIK5 GSK3A KLC1 MAGEA1 MDM4 MGAT4B MKRN3 MUTYH MYL2 NINL PHF23 RNF111 RXRG TERF1 TNFRSF10C TRIM17 TRIM74 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2H UBE2I UBE2J1 UBE2K UBE2N UBE2W UEVLD USP2 USP21 VPS11 XAF1 ZMAT4	19 interacting genes: HGS LGALS3 LGALS8 LRSAM1 MEOX2 MNAT1 TRAF6 TRIM39 TRIM41 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2H UBE2N UBE2W USP15
Entrez ID		90678	51127
HPRD ID		14325	05839
Ensembl ID		ENSG00000148356	ENSG00000162931
Uniprot IDs		A0A024R870 Q6UWE0	A0A024R3R3 B3KP04 Q9Y577
PDB IDs
Enriched GO Terms of Interacting Partners?
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