TAF1A and ANP32A

Data Source:
BioGRID (pull down, affinity chromatography technology)

		TAF1A	ANP32A
Description		TATA-box binding protein associated factor, RNA polymerase I subunit A	acidic nuclear phosphoprotein 32 family member A
Image		No pdb structure
GO Annotations	Cellular Component	RNA Polymerase I Transcription Regulator Complex Nucleoplasm Microtubule Cytoskeleton	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Protein Binding	RNA Binding Protein Binding Histone Binding
	Biological Process	Transcription By RNA Polymerase I Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription By RNA Polymerase II Positive Regulation Of Gene Expression, Epigenetic	Nucleocytoplasmic Transport Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of MRNA Stability
Pathways		SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	HuR (ELAVL1) binds and stabilizes mRNA
Drugs
Diseases
GWAS		Trunk fat mass ( 28552196)	Esophageal cancer ( 21642993)
Interacting Genes		20 interacting genes: ANP32A ESR1 H2AC20 H2BC21 H3-4 H3C1 H4-16 H4C1 JMJD6 NKAPD1 POLR1G RRN3 RUNX2 SET TAF12 TAF1B TAF1C TBP TP53 UBTF	29 interacting genes: ADAP1 APEX1 ATXN1 AXIN1 CHAF1A E4F1 ELAVL1 H2AC20 H2BC21 H3-4 H3C1 H3C15 H4-16 H4C1 HSPB3 KPNA1 KPNA5 KPNA6 LHX3 MAP1B NSFL1C PCBP1 PGR PPARG PTPRC SET TAF1A THRB XPO1
Entrez ID		9015	8125
HPRD ID		05362	09014
Ensembl ID		ENSG00000143498	ENSG00000140350
Uniprot IDs		A8K4K5 B4DS21 Q15573	A0A384P5U2 P39687
PDB IDs			2JE0 2JE1 4XOS
Enriched GO Terms of Interacting Partners?
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