TAF1A and RRN3

Data Source:
BioGRID (pull down)

		TAF1A	RRN3
Description		TATA-box binding protein associated factor, RNA polymerase I subunit A	RRN3 homolog, RNA polymerase I transcription factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	RNA Polymerase I Transcription Regulator Complex Nucleoplasm Microtubule Cytoskeleton	Nucleus Nucleoplasm Nucleolus
	Molecular Function	DNA Binding Protein Binding	RNA Polymerase I Core Binding RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I General Transcription Initiation Factor Activity
	Biological Process	Transcription By RNA Polymerase I Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription By RNA Polymerase II Positive Regulation Of Gene Expression, Epigenetic	RNA Polymerase I Preinitiation Complex Assembly Transcription Initiation From RNA Polymerase I Promoter Positive Regulation Of Neuron Projection Development
Pathways		SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape
Drugs
Diseases
GWAS		Trunk fat mass ( 28552196)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Fruit consumption ( 32066663) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Triglyceride levels ( 32154731)
Interacting Genes		20 interacting genes: ANP32A ESR1 H2AC20 H2BC21 H3-4 H3C1 H4-16 H4C1 JMJD6 NKAPD1 POLR1G RRN3 RUNX2 SET TAF12 TAF1B TAF1C TBP TP53 UBTF	10 interacting genes: CCNE1 CDK2 EIF3L MYO1C POLR1A POLR1B PPP2R2A TAF1A TAF1B TAF1C
Entrez ID		9015	54700
HPRD ID		05362	12004
Ensembl ID		ENSG00000143498	ENSG00000085721
Uniprot IDs		A8K4K5 B4DS21 Q15573	B7ZB55 F5H148 Q9NYV6
PDB IDs
Enriched GO Terms of Interacting Partners?
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