BTRC and E2F1

  • Data Source:
  • BioGRID (enzymatic study)

BTRC

E2F1

Description beta-transducin repeat containing E3 ubiquitin protein ligase E2F transcription factor 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Diastolic blood pressure ( 30224653)
  • Red blood cell count ( 29403010)
  • Red cell distribution width ( 32888494)
  • Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes 82 interacting genes: AGO2 AMER1 ATF4 AXIN1 AXIN2 BORA CCND1 CCNE1 CDC25A CDC34 CDK1 CENPW CHPF CHUK CP CTNNB1 CUL1 DBN1 DEPTOR DLGAP5 E2F1 FBXW11 FBXW2 FOXO3 FZR1 GHR GLI2 GLI3 GSK3B HIPK2 HNRNPC HNRNPK HNRNPU ICE1 IL10RA JUP KDR KMT5A LPCAT1 MCL1 MDM2 MYB MYC NFE2 NFKB1 NFKB2 NFKBIA NFKBIB NHSL2 PAQR3 PCDH8 PDCD4 PER2 PLK4 PRDX1 PSMA3 PSMD4 RASSF5 RCAN1 RELA RNF7 SKP1 SMAD3 SMAD4 SMURF1 SMURF2 SUFU TACC1 TAZ TIAM1 TP63 TRIB2 TRIM36 TRIM9 TSPAN15 UBC UBE2D2 UBE2R2 UBQLN2 WEE1 XRCC1 ZC3H12A 82 interacting genes: ARID3A ATAD2 ATM ATR BIN1 BIRC2 BRCA1 BRD2 BRMS1 BTRC CCNA1 CCNA2 CDK1 CDK2 CDK3 CDK7 CDKN2A CEBPE CHEK2 CREBBP CTDP1 CUL1 CUL2 DDB2 DIABLO E2F6 EP300 ERCC3 FHL2 GSK3B GTF2H1 HCFC1 IGF1 KAT5 KDM1A MDM2 MDM4 MGA MNAT1 MTA1 MYBL2 NCOA3 NCOA6 NCOR2 NDN NFKB1 NPDC1 NRIP1 NSMCE3 PARP1 PHB PKIB PRDM2 PURA RARA RB1 RBL1 RNF126 RNF144A SERTAD2 SETD7 SIRT1 SKP2 SP1 SP2 SP3 SP4 SPIB STAT1 STOML1 TBP TEAD3 TFDP1 TFDP2 TOPBP1 TP53 TP53BP1 TRRAP UBE3A UCHL5 VHL YWHAQ
Entrez ID 8945 1869
HPRD ID 04596 01806
Ensembl ID ENSG00000166167 ENSG00000101412
Uniprot IDs A0A0S2Z4P6 B2R8L3 B7Z3H4 Q68DS0 Q9Y297 Q01094 Q9BSD8
PDB IDs 1P22 2P64 6M90 6M91 6M92 6M93 6M94 6TTU 1H24 1O9K 2AZE 5M9N 5M9O 6G0P 6ULS
Enriched GO Terms of Interacting Partners?
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