BTRC and XRCC1

  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

BTRC

XRCC1

Description beta-transducin repeat containing E3 ubiquitin protein ligase X-ray repair cross complementing 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Diastolic blood pressure ( 30224653)
  • Red blood cell count ( 29403010)
  • Red cell distribution width ( 32888494)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Apolipoprotein B levels ( 32203549)
  • Height ( 31562340)
  • LDL cholesterol levels ( 32203549)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
Interacting Genes 82 interacting genes: AGO2 AMER1 ATF4 AXIN1 AXIN2 BORA CCND1 CCNE1 CDC25A CDC34 CDK1 CENPW CHPF CHUK CP CTNNB1 CUL1 DBN1 DEPTOR DLGAP5 E2F1 FBXW11 FBXW2 FOXO3 FZR1 GHR GLI2 GLI3 GSK3B HIPK2 HNRNPC HNRNPK HNRNPU ICE1 IL10RA JUP KDR KMT5A LPCAT1 MCL1 MDM2 MYB MYC NFE2 NFKB1 NFKB2 NFKBIA NFKBIB NHSL2 PAQR3 PCDH8 PDCD4 PER2 PLK4 PRDX1 PSMA3 PSMD4 RASSF5 RCAN1 RELA RNF7 SKP1 SMAD3 SMAD4 SMURF1 SMURF2 SUFU TACC1 TAZ TIAM1 TP63 TRIB2 TRIM36 TRIM9 TSPAN15 UBC UBE2D2 UBE2R2 UBQLN2 WEE1 XRCC1 ZC3H12A 18 interacting genes: APEX1 APLF APTX BRCA1 BTRC CSNK2A1 CSNK2A2 LIG3 NEIL1 OGG1 PARP1 PARP2 PCNA PNKP POLB RNF146 TOPORS UBE2I
Entrez ID 8945 7515
HPRD ID 04596 01909
Ensembl ID ENSG00000166167 ENSG00000073050
Uniprot IDs A0A0S2Z4P6 B2R8L3 B7Z3H4 Q68DS0 Q9Y297 B2RCY5 P18887 Q59HH7
PDB IDs 1P22 2P64 6M90 6M91 6M92 6M93 6M94 6TTU 1CDZ 1XNA 1XNT 2D8M 2W3O 3K75 3K77 3LQC 5E6Q 5W7X 5W7Y
Enriched GO Terms of Interacting Partners?
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