SKAP2 and FASLG

  • Data Source:
  • BioGRID (unspecified method)

SKAP2

FASLG

Description src kinase associated phosphoprotein 2 Fas ligand
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Chronic venous disease ( 28374850)
  • Disease free survival in colon cancer ( 31811950)
  • Erosive tooth wear (severe vs non-severe) ( 29898447)
  • Erosive tooth wear (severe vs none or mild) ( 29898447)
  • FEV1 ( 30804560)
  • Lung function (FVC) ( 30804560)
  • Lymphocyte counts ( 32888494)
  • Lymphocyte percentage of white cells ( 32888494)
  • Macular thickness ( 30535121)
  • Monocyte count ( 32888494)
  • Peak expiratory flow ( 30804560)
  • Small cell lung carcinoma ( 28604730)
  • Survival in colon cancer ( 31811950)
  • Systemic lupus erythematosus ( 28714469)
Interacting Genes 20 interacting genes: APP BLK DNAJB6 FAM102A FASLG FGR FRK FYB1 FYN HCK KHDRBS1 LCK LYN NCK2 PRAM1 PTK2B SRC SRMS TGFBR1 YES1 82 interacting genes: APBB1 ARHGAP9 BAIAP2L1 BTK CACNB3 CACNB4 CRK CYSRT1 DAXX DLG2 DMD DNMBP DOCK4 ECM1 EPS8L3 EZR FADD FAS FGR FN1 FNBP1 FYB1 FYN GRAP GRAP2 GRB2 HCK IHO1 ITK ITSN2 KALRN KMT2A KRT33B KRT40 KRTAP11-1 KRTAP12-3 LCK LYN MACC1 MIA MMP7 MPP4 MYO15A NCF1 NCK1 NCK2 NCKIPSD NOTCH2NLA OSTF1 PACSIN2 PDCD6 PIK3CA PIK3R1 PIN1 PPIAP11 PRPF40A PSTPIP1 PTPN13 RGS20 RIMBP3C SAMSN1 SEC23A SH3GL3 SH3PXD2A SH3PXD2B SH3RF2 SKAP2 SNX33 SNX9 SORBS3 SPTA1 SRC SRGAP1 SRGAP2 SRGAP3 SUMO1 TEC TJP3 TNFRSF6B TNS2 TRIP6 YES1
Entrez ID 8935 356
HPRD ID 05558 00610
Ensembl ID ENSG00000005020 ENSG00000117560
Uniprot IDs B7Z5R3 O75563 P48023 Q53ZZ1
PDB IDs 3OMH 1BZI 4MSV 5L19 5L36
Enriched GO Terms of Interacting Partners?
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