CACNA1G and RANBP9

Data Source:
BioGRID (two hybrid)

		CACNA1G	RANBP9
Description		calcium voltage-gated channel subunit alpha1 G	RAN binding protein 9
Image
GO Annotations	Cellular Component	Voltage-gated Sodium Channel Complex Cytoplasm Plasma Membrane Voltage-gated Calcium Channel Complex Neuron Projection Synapse	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane Nuclear Body
	Molecular Function	Voltage-gated Sodium Channel Activity Low Voltage-gated Calcium Channel Activity Voltage-gated Calcium Channel Activity Involved In AV Node Cell Action Potential Voltage-gated Calcium Channel Activity Involved SA Node Cell Action Potential Scaffold Protein Binding	Protein Binding Enzyme Binding
	Biological Process	Chemical Synaptic Transmission Response To Nickel Cation Neuronal Action Potential Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Regulation Of Membrane Potential Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Calcium Ion Import Calcium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Involved In Contraction Membrane Depolarization During Action Potential SA Node Cell Action Potential AV Node Cell Action Potential SA Node Cell To Atrial Cardiac Muscle Cell Signaling AV Node Cell To Bundle Of His Cell Signaling Membrane Depolarization During AV Node Cell Action Potential Membrane Depolarization During SA Node Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction	MAPK Cascade Cytoskeleton Organization Microtubule Nucleation Cell Surface Receptor Signaling Pathway Axon Guidance Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Amyloid Precursor Protein Catabolic Process
Pathways		NCAM1 interactions	L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling
Drugs		Ergocalciferol Enflurane Trimethadione Spironolactone Cinnarizine Ethosuximide Verapamil Zonisamide Nifedipine Mibefradil Flunarizine Methsuximide Cannabidiol Trimebutine Benidipine Manidipine Butamben Bioallethrin Bioallethrin Medical Cannabis Nabiximols
Diseases
GWAS		Adventurousness ( 30643258) Alzheimer's disease (cognitive decline) ( 23535033) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) PR interval ( 32439900) Total cholesterol levels ( 30498476)	Breast cancer ( 29059683 23535729)
Interacting Genes		2 interacting genes: RANBP9 UBQLN4	56 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 CACNA1G CALB1 CBS CCND1 CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LMNA MAPK6 MET MPHOSPH8 NCOA6 NCOR2 NSRP1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 YPEL5
Entrez ID		8913	10048
HPRD ID		04961	04835
Ensembl ID		ENSG00000006283	ENSG00000010017
Uniprot IDs		O43497	A0A024QZW3 Q96S59
PDB IDs		6KZO 6KZP	5JI7 5JI9 5JIU
Enriched GO Terms of Interacting Partners?
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