TAX1BP1 and TRIM45

Data Source:
BioGRID (two hybrid)

		TAX1BP1	TRIM45
Description		Tax1 binding protein 1	tripartite motif containing 45
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GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Chromatin Nucleoplasm Cytosol Intercellular Bridge
	Molecular Function	Protein Binding Kinase Binding Metal Ion Binding	Ubiquitin-protein Transferase Activity Zinc Ion Binding
	Biological Process	Apoptotic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process	Protein Ubiquitination Positive Regulation Of Transcription, DNA-templated Bone Development
Pathways		Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling	Interferon gamma signaling
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)
Interacting Genes		75 interacting genes: ARHGAP1 AZI2 C18orf25 CBX8 COG7 CWF19L2 CXXC1 DAXX DAZAP2 DSTN EMILIN1 FAM161A FAM168A FAM189A2 FAM90A1 FOXC2 GABARAP GABARAPL1 GABARAPL2 IGFN1 IKBKG KANK2 KAT5 KIF5B L3MBTL2 LGALS8 LITAF LMO3 LNX1 LRATD2 MAP1LC3B MAP1LC3C MRPL11 MRPL53 NMRK1 NTAQ1 ORC5 PIBF1 PLEKHB2 PLEKHN1 POLR1C RAB18 RAD18 RAD23B RAD54L2 RB1CC1 RIPK1 RNF11 SCNM1 SH3GLB1 SSX2 STARD13 TBC1D15 TBC1D17 TCAF1 TCEA2 TCL1A TNFAIP3 TNIP1 TNIP3 TRAF4 TRAF6 TRAPPC6A TRIM14 TRIM45 TSEN2 TSG101 TSHZ3 UBA52 UBASH3A UBB UBC UBTFL1 USP2 ZNF446	17 interacting genes: CDC42 GABARAPL2 MED10 MEOX2 PTGES3L-AARSD1 TAX1BP1 TEPSIN TFIP11 UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 ZMYND19
Entrez ID		8887	80263
HPRD ID		05618	15562
Ensembl ID		ENSG00000106052	ENSG00000134253
Uniprot IDs		B4DSG5 Q86VP1	Q9H8W5
PDB IDs		2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G	2DS4
Enriched GO Terms of Interacting Partners?
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