TRIM45 and MED10

		TRIM45	MED10
Description		tripartite motif containing 45	mediator complex subunit 10
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytosol Intercellular Bridge	Ubiquitin Ligase Complex Chromatin Nucleoplasm Mediator Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Ubiquitination Positive Regulation Of Transcription, DNA-templated Bone Development	Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Interferon gamma signaling	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS
Interacting Genes		17 interacting genes: CDC42 GABARAPL2 MED10 MEOX2 PTGES3L-AARSD1 TAX1BP1 TEPSIN TFIP11 UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 ZMYND19	12 interacting genes: ABI2 ARHGDIG ESR1 ESR2 FUCA1 HNF4A KDM4B MOB4 NAP1L1 PEBP1 SYCE1L TRIM45
Entrez ID		80263	84246
HPRD ID		15562	14680
Ensembl ID		ENSG00000134253	ENSG00000133398
Uniprot IDs		Q9H8W5	Q9BTT4
PDB IDs		2DS4
Enriched GO Terms of Interacting Partners?
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