TAX1BP1 and TBC1D15

Data Source:
BioGRID (two hybrid)

		TAX1BP1	TBC1D15
Description		Tax1 binding protein 1	TBC1 domain family member 15
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Extracellular Region Cytoplasm
	Molecular Function	Protein Binding Kinase Binding Metal Ion Binding	GTPase Activator Activity Protein Binding
	Biological Process	Apoptotic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process	Intracellular Protein Transport Regulation Of GTPase Activity Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling	TBC/RABGAPs
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)	Inferior parietal cortex volume ( 31530798) Metabolite levels ( 23823483)
Interacting Genes		75 interacting genes: ARHGAP1 AZI2 C18orf25 CBX8 COG7 CWF19L2 CXXC1 DAXX DAZAP2 DSTN EMILIN1 FAM161A FAM168A FAM189A2 FAM90A1 FOXC2 GABARAP GABARAPL1 GABARAPL2 IGFN1 IKBKG KANK2 KAT5 KIF5B L3MBTL2 LGALS8 LITAF LMO3 LNX1 LRATD2 MAP1LC3B MAP1LC3C MRPL11 MRPL53 NMRK1 NTAQ1 ORC5 PIBF1 PLEKHB2 PLEKHN1 POLR1C RAB18 RAD18 RAD23B RAD54L2 RB1CC1 RIPK1 RNF11 SCNM1 SH3GLB1 SSX2 STARD13 TBC1D15 TBC1D17 TCAF1 TCEA2 TCL1A TNFAIP3 TNIP1 TNIP3 TRAF4 TRAF6 TRAPPC6A TRIM14 TRIM45 TSEN2 TSG101 TSHZ3 UBA52 UBASH3A UBB UBC UBTFL1 USP2 ZNF446	9 interacting genes: CALCOCO1 CEP63 FIS1 OPTN RAB5A RAB5B RAB5C TAX1BP1 UBC
Entrez ID		8887	64786
HPRD ID		05618	15470
Ensembl ID		ENSG00000106052	ENSG00000121749
Uniprot IDs		B4DSG5 Q86VP1	A8K8E1 Q8TC07
PDB IDs		2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G
Enriched GO Terms of Interacting Partners?
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