PRKRA and PITPNM1

Data Source:
HPRD (two hybrid)

		PRKRA	PITPNM1
Description		protein activator of interferon induced protein kinase EIF2AK2	phosphatidylinositol transfer protein membrane associated 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm RISC-loading Complex	Cytoplasm Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Membrane Midbody Cleavage Furrow Golgi Cisterna Membrane Intracellular Membrane-bounded Organelle Cell Body
	Molecular Function	RNA Binding Double-stranded RNA Binding Protein Binding Enzyme Activator Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Pre-miRNA Binding	Calcium Ion Binding Protein Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transfer Activity Receptor Tyrosine Kinase Binding Phosphatidylcholine Binding Phosphatidylinositol Binding Phosphatidic Acid Binding
	Biological Process	Protein Phosphorylation Immune Response Negative Regulation Of Cell Population Proliferation Response To Virus MiRNA Metabolic Process Viral Process Production Of SiRNA Involved In RNA Interference Pre-miRNA Processing Cellular Response To Oxidative Stress Production Of MiRNAs Involved In Gene Silencing By MiRNA Outer Ear Morphogenesis Middle Ear Morphogenesis Skeletal System Morphogenesis Regulation Of Catalytic Activity Protein Stabilization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Lipid Metabolic Process Phosphatidylinositol Biosynthetic Process Brain Development Phototransduction Protein Transport Phospholipid Transport Intermembrane Lipid Transfer
Pathways		MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis	Synthesis of PI
Drugs
Diseases		Primary torsion dystonia (PTD)
GWAS		Inflammatory skin disease ( 25574825) Multiple sclerosis (OCB status) ( 23472185) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183)	Refractive error ( 32231278)
Interacting Genes		28 interacting genes: ADARB1 AGO2 CEBPZ CEP126 COPS6 DICER1 EHHADH EIF2AK2 GDF9 LNX1 LYAR NKRF PIAS2 POLR2G RABEPK RB1 SETDB1 SHC1 SNX5 STAU1 STRBP TARBP2 TIRAP TP53 ZFP28 ZMAT3 ZMAT4 ZNF746	5 interacting genes: CDK1 PLK1 PTK2B RHOA TFCP2
Entrez ID		8575	9600
HPRD ID		04573	07497
Ensembl ID		ENSG00000180228	ENSG00000110697
Uniprot IDs		B4DJC7 O75569	A0A024R5I7 B2R787 O00562
PDB IDs		2DIX
Enriched GO Terms of Interacting Partners?
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