DPY30 and FAM136A

Data Source:
BioGRID (two hybrid)

		DPY30	FAM136A
Description		dpy-30 histone methyltransferase complex regulatory subunit	family with sequence similarity 136 member A
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Golgi Apparatus Trans-Golgi Network Histone Methyltransferase Complex MLL3/4 Complex Set1C/COMPASS Complex	Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Chromatin Silencing At Telomere Endosomal Transport Regulation Of Megakaryocyte Differentiation Histone H3-K4 Methylation
Pathways		PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS		Inflammatory biomarkers ( 24182552) Interleukin-18 levels ( 31584380) Male-pattern baldness ( 28196072)	Acne (severe) ( 24927181) LDL cholesterol ( 30275531) Male-pattern baldness ( 28196072) Metabolite levels ( 23823483) Response to citalopram or escitalopram in depression ( 27622933) Total cholesterol levels ( 30275531)
Interacting Genes		33 interacting genes: AK8 AKAP14 ARFGEF1 ASH2L BCAS4 BEND3 CDK17 CFAP91 CHMP2B CREB3L3 DYDC1 DYDC2 FAM136A GPATCH2 GTF2I H3-4 ICA1L KMT2C MRFAP1 OTX1 PRPF3 PRRC2B PSMC3 PSMD14 PXN RSPH3 SETD1A TMCC2 TSPY10 TSPY2 TSPY3 UBC ZFYVE19	11 interacting genes: ANKRD11 DPY30 MAGEB4 MBD3 MEIS2 NTAQ1 P4HA3 PSMB1 RUNX1T1 SMARCD1 TTC19
Entrez ID		84661	84908
HPRD ID		17434	07866
Ensembl ID		ENSG00000162961	ENSG00000035141
Uniprot IDs		B4DIS3 Q9C005	B0AZT6 E7EQY1 Q96C01
PDB IDs		3G36 4RIQ 4RT4 4RTA 6E2H 6PWV
Enriched GO Terms of Interacting Partners?
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