DPY30 and ZFYVE19

Data Source:
BioGRID (two hybrid)

		DPY30	ZFYVE19
Description		dpy-30 histone methyltransferase complex regulatory subunit	zinc finger FYVE-type containing 19
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Golgi Apparatus Trans-Golgi Network Histone Methyltransferase Complex MLL3/4 Complex Set1C/COMPASS Complex	Cytoplasm Centrosome Midbody Cleavage Furrow Flemming Body
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding
	Biological Process	Chromatin Silencing At Telomere Endosomal Transport Regulation Of Megakaryocyte Differentiation Histone H3-K4 Methylation	Abscission Negative Regulation Of Cytokinesis Mitotic Cytokinesis Checkpoint Cell Division
Pathways		PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS		Inflammatory biomarkers ( 24182552) Interleukin-18 levels ( 31584380) Male-pattern baldness ( 28196072)	Anxiety and stress-related disorders ( 31116379) Malaria ( 31844061)
Interacting Genes		33 interacting genes: AK8 AKAP14 ARFGEF1 ASH2L BCAS4 BEND3 CDK17 CFAP91 CHMP2B CREB3L3 DYDC1 DYDC2 FAM136A GPATCH2 GTF2I H3-4 ICA1L KMT2C MRFAP1 OTX1 PRPF3 PRRC2B PSMC3 PSMD14 PXN RSPH3 SETD1A TMCC2 TSPY10 TSPY2 TSPY3 UBC ZFYVE19	10 interacting genes: AXIN1 CAPN7 CCHCR1 DPY30 HTT MITD1 TRIM55 TRIM63 VPS4B ZDHHC17
Entrez ID		84661	84936
HPRD ID		17434	15731
Ensembl ID		ENSG00000162961	ENSG00000166140
Uniprot IDs		B4DIS3 Q9C005	Q96K21
PDB IDs		3G36 4RIQ 4RT4 4RTA 6E2H 6PWV
Enriched GO Terms of Interacting Partners?
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