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LZTS2 and CBX8
Data Source:
BioGRID
(two hybrid)
LZTS2
CBX8
Description
leucine zipper tumor suppressor 2
chromobox 8
Image
No pdb structure
GO Annotations
Cellular Component
Centrosome
Cytosol
Microtubule
Plasma Membrane
Midbody
Vesicle
Chromatin
Heterochromatin
Nucleus
Nucleoplasm
PcG Protein Complex
PRC1 Complex
Molecular Function
Protein Binding
Single-stranded RNA Binding
Protein Binding
Methylated Histone Binding
Ubiquitin-protein Transferase Activator Activity
Biological Process
Mitotic Cytokinesis
Negative Regulation Of Cell Population Proliferation
Wnt Signaling Pathway
Microtubule Severing
Nuclear Export
Spindle Midzone Assembly
Primary Ureteric Bud Growth
Ureter Morphogenesis
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Nucleus
Negative Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Cell Population Proliferation
Histone Ubiquitination
Positive Regulation Of Collagen Biosynthetic Process
Positive Regulation Of DNA Repair
Regulation Of Catalytic Activity
Cellular Response To Hydrogen Peroxide
Pathways
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Drugs
Diseases
GWAS
Ejection fraction in Tripanosoma cruzi seropositivity (
24324551
)
Regular attendance at a pub or social club (
29970889
)
Brain morphology (MOSTest) (
32665545
)
General risk tolerance (MTAG) (
30643258
)
Plateletcrit (
32888494
)
Risk-taking tendency (4-domain principal component model) (
30643258
)
Smoking status (ever vs never smokers) (
30643258
)
Youthful appearance (self-reported) (
32339537
)
Interacting Genes
217 interacting genes:
ABI2
ABT1
AEN
ANKRD11
ANKRD36BP1
AP1M1
ARMC7
ARNT2
ATPAF2
BAHD1
BEX2
BMS1P1
BYSL
C1orf109
C2CD6
C8orf33
CABP5
CARD9
CATSPER1
CBX8
CCDC187
CCDC198
CCDC85B
CCNC
CCNG1
CCNK
CDC23
CDK18
CDKL3
CDKN1A
CEP57L1
CFAP206
CHCHD3
CHIC2
CLIP4
CNNM3
COPB1
CSNK1D
CWF19L2
DCUN1D1
DGCR6
DGCR6L
DUSP4
DYRK2
EHHADH
EIF3D
EIF4E2
EXOSC5
FAM107A
FAM124B
FAM161A
FAM214B
FAM221B
FAM50B
FAM74A4
FAM90A1
FANCL
FEM1C
FGF12
FKBP6
FNDC11
FRG1
FRMD6
GADD45GIP1
GATA1
GCC1
GEM
GFI1B
GIPC2
GLIDR
GLYCTK
GMCL2
GNL3L
GPANK1
GPATCH2L
GRB2
HLA-DPB1
HM13
HOMER2
HOXB9
HSPD1
IGFN1
INO80B
IQCE
IQCN
KAT5
KAZN
KIF9
KIFC3
KPNA2
LASP1
LCK
LIN37
LMO1
LMO2
LMO3
MAB21L3
MAGEB4
MAPK1
MEMO1
MID2
MORF4L1
MORF4L2
MORN3
MOS
MTA1
MYOZ1
NCBP2
NCK2
NDE1
NEBL
NEK6
NINL
NIP7
NTAQ1
OTUB2
PAK5
PATZ1
PHF1
PHF19
PITX1
PKP4
PLEKHN1
POLDIP3
POLR1C
PPP1R16A
PPP1R18
PQBP1
PRKAA2
PRKAB2
PRPF18
PRPF31
PRR35
PSMA1
QARS1
RAC1
RAD51D
RAMAC
RBFOX1
RBM15
RBM41
RBPMS
RCOR3
RHNO1
RHOXF2
RIN1
RNF32
RNF41
RTP5
RUNX1T1
SCNM1
SH2D4A
SH3KBP1
SH3RF2
SHFL
SLC15A3
SLC25A6
SLC39A14
SLU7
SMARCB1
SMARCD1
SMIM3
SNHG11
SNW1
SNX31
SPATA24
SPATC1L
SPG7
SRSF2
STAC
SUPV3L1
SUV39H1
SYT17
TBC1D7
TCEA2
TEAD4
THAP10
THAP7
TLE5
TNIP3
TRAF2
TRIM29
TRIM42
TSNAX
TSSK2
TSSK3
TTC23
TTLL10
TXNL4A
UBASH3A
UBASH3B
USF2
USP2
UTP14C
VEZF1
WT1-AS
YTHDC1
ZBTB25
ZBTB38
ZC2HC1C
ZGPAT
ZKSCAN3
ZMAT1
ZMAT2
ZMYND19
ZNF124
ZNF20
ZNF250
ZNF408
ZNF417
ZNF426
ZNF446
ZNF490
ZNF512B
ZNF572
ZNF581
ZNF648
87 interacting genes:
ABLIM3
BACH2
BANP
BMI1
CALCOCO2
CARD10
CARD9
CCDC136
CCDC57
CEP70
DVL3
EEF1G
FHL3
FSD2
FXR1
GIGYF1
GOLGA2
GOLGA6L9
GPRASP2
GRIPAP1
H3-4
HAP1
HMBOX1
HOMEZ
HOOK2
HSF2BP
IKZF1
JADE2
JAKMIP1
KANK2
KAT5
KAT7
KCTD9
KIFC3
KRT31
KRT34
KRT40
LSM2
LZTS2
MB21D2
MCC
MDFI
MID2
MLLT1
MLLT3
MTUS2
NAB2
PAXIP1
PCGF5
PHACTR1
PIBF1
PICK1
PIH1D2
PLEKHF2
PNMA1
PNMA2
POLR1C
PRDM6
PRKAR1B
RASSF3
RING1
RPGRIP1
SESTD1
SETDB1
SOX5
TAX1BP1
TEPSIN
TFCP2
TFIP11
TRAF2
TRIB3
TRIM23
TRIM27
TRIM54
TSC22D4
TSGA10
TTC23
UNC119
USH1G
USP11
USP7
VIM
ZBTB14
ZBTB8A
ZBTB9
ZNF185
ZRANB1
Entrez ID
84445
57332
HPRD ID
14341
13006
Ensembl ID
ENSG00000107816
ENSG00000141570
Uniprot IDs
B4DP66
Q9BRK4
Q9HC52
PDB IDs
2N4Q
3I91
5EQ0
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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