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CBX8 and PIH1D2
Data Source:
BioGRID
(two hybrid)
CBX8
PIH1D2
Description
chromobox 8
PIH1 domain containing 2
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Heterochromatin
Nucleus
Nucleoplasm
PcG Protein Complex
PRC1 Complex
Cytoplasm
R2TP Complex
Ribonucleoprotein Complex
Molecular Function
Single-stranded RNA Binding
Protein Binding
Methylated Histone Binding
Ubiquitin-protein Transferase Activator Activity
Protein Binding
Small GTPase Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Cell Population Proliferation
Histone Ubiquitination
Positive Regulation Of Collagen Biosynthetic Process
Positive Regulation Of DNA Repair
Regulation Of Catalytic Activity
Cellular Response To Hydrogen Peroxide
Box C/D SnoRNP Assembly
RRNA Processing
Pathways
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
General risk tolerance (MTAG) (
30643258
)
Plateletcrit (
32888494
)
Risk-taking tendency (4-domain principal component model) (
30643258
)
Smoking status (ever vs never smokers) (
30643258
)
Youthful appearance (self-reported) (
32339537
)
Brain morphology (MOSTest) (
32665545
)
Interacting Genes
87 interacting genes:
ABLIM3
BACH2
BANP
BMI1
CALCOCO2
CARD10
CARD9
CCDC136
CCDC57
CEP70
DVL3
EEF1G
FHL3
FSD2
FXR1
GIGYF1
GOLGA2
GOLGA6L9
GPRASP2
GRIPAP1
H3-4
HAP1
HMBOX1
HOMEZ
HOOK2
HSF2BP
IKZF1
JADE2
JAKMIP1
KANK2
KAT5
KAT7
KCTD9
KIFC3
KRT31
KRT34
KRT40
LSM2
LZTS2
MB21D2
MCC
MDFI
MID2
MLLT1
MLLT3
MTUS2
NAB2
PAXIP1
PCGF5
PHACTR1
PIBF1
PICK1
PIH1D2
PLEKHF2
PNMA1
PNMA2
POLR1C
PRDM6
PRKAR1B
RASSF3
RING1
RPGRIP1
SESTD1
SETDB1
SOX5
TAX1BP1
TEPSIN
TFCP2
TFIP11
TRAF2
TRIB3
TRIM23
TRIM27
TRIM54
TSC22D4
TSGA10
TTC23
UNC119
USH1G
USP11
USP7
VIM
ZBTB14
ZBTB8A
ZBTB9
ZNF185
ZRANB1
69 interacting genes:
ANKRD11
BAG3
BANP
CBLL2
CBX8
CCNL2
CDC23
CDCA8
CDKL3
CFAP206
COMMD3
CT55
CTAG1A
CTAG1B
DES
DPH3
DSCAM
EIF4A2
EXOSC5
FRS3
GFAP
GMCL1
GPRASP2
HES7
HSF4
IGF2BP3
IQUB
ITGB3BP
KRTAP12-2
KRTAP12-4
LAP3
LMNB1
MCCD1
MDFI
MED20
MISP
MRFAP1L1
MVP
NFIL3
NHSL2
NOTO
NTAQ1
NXF1
PBX4
PLEKHJ1
POLR1C
PRDM6
PRMT3
RALA
REL
RSPO4
SDCBP
SERTAD1
SLPI
SPRED1
SSX3
SUOX
TAF6
TASOR2
TBATA
TCEA2
TNNI1
TTC23
ZBTB1
ZMAT5
ZNF185
ZNF417
ZNF438
ZNF688
Entrez ID
57332
120379
HPRD ID
13006
14021
Ensembl ID
ENSG00000141570
ENSG00000150773
Uniprot IDs
Q9HC52
Q8WWB5
PDB IDs
2N4Q
3I91
5EQ0
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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