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LZTS2 and EIF3D
Data Source:
BioGRID
(two hybrid)
LZTS2
EIF3D
Description
leucine zipper tumor suppressor 2
eukaryotic translation initiation factor 3 subunit D
Image
No pdb structure
GO Annotations
Cellular Component
Centrosome
Cytosol
Microtubule
Plasma Membrane
Midbody
Vesicle
Cytosol
Eukaryotic Translation Initiation Factor 3 Complex
Membrane
Eukaryotic 43S Preinitiation Complex
Eukaryotic 48S Preinitiation Complex
Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
Molecular Function
Protein Binding
RNA Binding
Translation Initiation Factor Activity
Protein Binding
MRNA Cap Binding
Biological Process
Mitotic Cytokinesis
Negative Regulation Of Cell Population Proliferation
Wnt Signaling Pathway
Microtubule Severing
Nuclear Export
Spindle Midzone Assembly
Primary Ureteric Bud Growth
Ureter Morphogenesis
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Nucleus
Formation Of Cytoplasmic Translation Initiation Complex
Cap-dependent Translational Initiation
Translational Initiation
Positive Regulation Of Translation
IRES-dependent Viral Translational Initiation
Viral Translational Termination-reinitiation
Positive Regulation Of MRNA Binding
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS
Ejection fraction in Tripanosoma cruzi seropositivity (
24324551
)
Regular attendance at a pub or social club (
29970889
)
Interacting Genes
217 interacting genes:
ABI2
ABT1
AEN
ANKRD11
ANKRD36BP1
AP1M1
ARMC7
ARNT2
ATPAF2
BAHD1
BEX2
BMS1P1
BYSL
C1orf109
C2CD6
C8orf33
CABP5
CARD9
CATSPER1
CBX8
CCDC187
CCDC198
CCDC85B
CCNC
CCNG1
CCNK
CDC23
CDK18
CDKL3
CDKN1A
CEP57L1
CFAP206
CHCHD3
CHIC2
CLIP4
CNNM3
COPB1
CSNK1D
CWF19L2
DCUN1D1
DGCR6
DGCR6L
DUSP4
DYRK2
EHHADH
EIF3D
EIF4E2
EXOSC5
FAM107A
FAM124B
FAM161A
FAM214B
FAM221B
FAM50B
FAM74A4
FAM90A1
FANCL
FEM1C
FGF12
FKBP6
FNDC11
FRG1
FRMD6
GADD45GIP1
GATA1
GCC1
GEM
GFI1B
GIPC2
GLIDR
GLYCTK
GMCL2
GNL3L
GPANK1
GPATCH2L
GRB2
HLA-DPB1
HM13
HOMER2
HOXB9
HSPD1
IGFN1
INO80B
IQCE
IQCN
KAT5
KAZN
KIF9
KIFC3
KPNA2
LASP1
LCK
LIN37
LMO1
LMO2
LMO3
MAB21L3
MAGEB4
MAPK1
MEMO1
MID2
MORF4L1
MORF4L2
MORN3
MOS
MTA1
MYOZ1
NCBP2
NCK2
NDE1
NEBL
NEK6
NINL
NIP7
NTAQ1
OTUB2
PAK5
PATZ1
PHF1
PHF19
PITX1
PKP4
PLEKHN1
POLDIP3
POLR1C
PPP1R16A
PPP1R18
PQBP1
PRKAA2
PRKAB2
PRPF18
PRPF31
PRR35
PSMA1
QARS1
RAC1
RAD51D
RAMAC
RBFOX1
RBM15
RBM41
RBPMS
RCOR3
RHNO1
RHOXF2
RIN1
RNF32
RNF41
RTP5
RUNX1T1
SCNM1
SH2D4A
SH3KBP1
SH3RF2
SHFL
SLC15A3
SLC25A6
SLC39A14
SLU7
SMARCB1
SMARCD1
SMIM3
SNHG11
SNW1
SNX31
SPATA24
SPATC1L
SPG7
SRSF2
STAC
SUPV3L1
SUV39H1
SYT17
TBC1D7
TCEA2
TEAD4
THAP10
THAP7
TLE5
TNIP3
TRAF2
TRIM29
TRIM42
TSNAX
TSSK2
TSSK3
TTC23
TTLL10
TXNL4A
UBASH3A
UBASH3B
USF2
USP2
UTP14C
VEZF1
WT1-AS
YTHDC1
ZBTB25
ZBTB38
ZC2HC1C
ZGPAT
ZKSCAN3
ZMAT1
ZMAT2
ZMYND19
ZNF124
ZNF20
ZNF250
ZNF408
ZNF417
ZNF426
ZNF446
ZNF490
ZNF512B
ZNF572
ZNF581
ZNF648
31 interacting genes:
ANKRD28
BEND5
CCDC125
CCDC57
CDC42
CEP70
CREBBP
DNAJB11
DVL3
EIF3G
EIF3J
EIF3L
EIF5
ERCC6
GOLGA6L9
HOMER3
HOOK2
HSF2BP
KIFC3
LZTS2
MORN3
MTUS2
PHLDA1
PICK1
POLR2G
REL
SAT1
TFIP11
TRIM23
TRIM27
ZRANB1
Entrez ID
84445
8664
HPRD ID
14341
04888
Ensembl ID
ENSG00000107816
ENSG00000100353
Uniprot IDs
B4DP66
Q9BRK4
O15371
PDB IDs
6YBD
6YBS
6ZMW
6ZON
6ZP4
6ZVJ
7A09
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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