NUDT22 and USP54

Data Source:
BioGRID (two hybrid)

		NUDT22	USP54
Description		nudix hydrolase 22	ubiquitin specific peptidase 54
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm
	Molecular Function	Protein Binding UDP-sugar Diphosphatase Activity Metal Ion Binding GDP-mannose Hydrolase Activity	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding
	Biological Process		Protein Deubiquitination Protein Phosphopantetheinylation
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Fruit consumption ( 32066663)	Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		22 interacting genes: ARID5A DDIT4L DNAL4 IKZF5 INCA1 KLHL26 LHX3 RUSC1 SAXO1 TCF4 TLE5 USP54 WDR54 ZBTB33 ZMYND12 ZNF143 ZNF19 ZNF343 ZNF398 ZNF581 ZNF648 ZNF655	88 interacting genes: ANKRD11 ANKS1A ARMC7 ATN1 ATXN1 ATXN1L ATXN7L2 BFSP2 BHLHE40 CARD10 CCDC13 CCDC24 CCNK CDC23 CHCHD2 CHERP CHMP1B CHMP2A CHMP2B CHMP4C CSTF2 CYSRT1 DMRT3 DOK6 DTX2 EIF4E2 EPM2AIP1 EXOC8 FAM124B FBXO17 FNDC3B FOXI1 GCM2 HGS HNF1B HNRNPF HOXC8 IGFN1 INSC KCTD9 LMO3 LNX1 MED25 MID2 NUDT22 NXT2 OIP5 OTX1 PCSK5 PHF1 PLA2G6 PLAC8 PLEKHN1 POLR1C PRDM6 PRKAB2 PRR35 QRICH1 RACK1 RAMAC RBPMS2 RHOBTB3 RNF208 SEC24A SHARPIN SHC3 SMARCD1 SMYD1 SNRPB SS18L1 STK16 TBX6 TCEA2 TEKT5 TENT5B TFAP2D TLE5 TNS2 TOLLIP TSEN15 TSSK3 TTC19 UBC USP2 VENTX ZCCHC14 ZNF148 ZNF76
Entrez ID		84304	159195
HPRD ID		14434	15641
Ensembl ID		ENSG00000149761	ENSG00000166348
Uniprot IDs		Q9BRQ3	B7Z7X1 Q70EL1
PDB IDs		5LF9 5LOR 5LOU 5R50 5R51 5R52 5R53 5R54 5R55 5R56 5R57 5R58 5R59 5R5A 5R5B 5R5C 5R5D 5R5E 5R5F 5R5G 5R5H 5R5I 5R5J 5R5K 5R5L 5R5M 5R5N 5R5O 5R5P 5R5Q 5R5R 5R5S 5RKZ
Enriched GO Terms of Interacting Partners?
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