USP54 and ZCCHC14

Data Source:
BioGRID (two hybrid)

		USP54	ZCCHC14
Description		ubiquitin specific peptidase 54	zinc finger CCHC-type containing 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding Phosphatidylinositol Binding
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation
Pathways
Drugs
Diseases
GWAS		Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Broad depression or schizophrenia ( 30626913) Hippocampal volume in mild cognitive impairment ( 29274321) Ischemic stroke ( 29531354) Ischemic stroke (small-vessel) ( 29531354) Major depressive disorder ( 22472876) Migraine ( 27182965 27322543) Neuroticism ( 29255261) Refractive error ( 32231278) Small vessel stroke ( 27997041) Stroke ( 29531354)
Interacting Genes		88 interacting genes: ANKRD11 ANKS1A ARMC7 ATN1 ATXN1 ATXN1L ATXN7L2 BFSP2 BHLHE40 CARD10 CCDC13 CCDC24 CCNK CDC23 CHCHD2 CHERP CHMP1B CHMP2A CHMP2B CHMP4C CSTF2 CYSRT1 DMRT3 DOK6 DTX2 EIF4E2 EPM2AIP1 EXOC8 FAM124B FBXO17 FNDC3B FOXI1 GCM2 HGS HNF1B HNRNPF HOXC8 IGFN1 INSC KCTD9 LMO3 LNX1 MED25 MID2 NUDT22 NXT2 OIP5 OTX1 PCSK5 PHF1 PLA2G6 PLAC8 PLEKHN1 POLR1C PRDM6 PRKAB2 PRR35 QRICH1 RACK1 RAMAC RBPMS2 RHOBTB3 RNF208 SEC24A SHARPIN SHC3 SMARCD1 SMYD1 SNRPB SS18L1 STK16 TBX6 TCEA2 TEKT5 TENT5B TFAP2D TLE5 TNS2 TOLLIP TSEN15 TSSK3 TTC19 UBC USP2 VENTX ZCCHC14 ZNF148 ZNF76	16 interacting genes: CYSRT1 FHL3 MYO15B MYOG NFIC PLEKHG4 PRR20A PRR20B PRR20C PRR20D PRR20E SMAD3 TENT4B TET2 TNS2 USP54
Entrez ID		159195	23174
HPRD ID		15641	18316
Ensembl ID		ENSG00000166348	ENSG00000140948
Uniprot IDs		B7Z7X1 Q70EL1	Q8WYQ9
PDB IDs
Enriched GO Terms of Interacting Partners?
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